Landscape analysis of m6A modification regulators related biological functions and immune characteristics in myasthenia gravis - PubMed
Source : https://pubmed.ncbi.nlm.nih.gov/36864526/
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Conclusions: Our findings suggested that m6A RNA modification had an important effect on immunity molecular mechanism of MG and provided a new perspective into understanding the pathogenesis of MG.
Association Between Myasthenia Gravis-Activities of Daily Living (MG-ADL) and EQ-5D-5L Utility Values: The Additional Effect of Efgartigimod on Utilities - Advances in Therapy
Source : https://link.springer.com/article/10.1007/s12325-023-02437-w
Introduction For patients with generalized myasthenia gravis (gMG), the association between symptom severity, often measured with the Myasthenia Gravis Activities of Daily Living (MG-ADL) instrument, and utility values is unknown....
Conclusions: Among patients with gMG, improvements in MG-ADL were significantly associated with higher utility values. MG-ADL scores alone were not sufficient to capture the utility gained from efgartigimod therapy.
Investigation of the Underlying Mechanism of Huangqi-Dangshen for Myasthenia Gravis Treatment via Molecular Docking and Network Pharmacology - PubMed
Source : https://pubmed.ncbi.nlm.nih.gov/36818231/
The herbal pairing of Huangqi and Dangshen (HD) is traditional Chinese herbal medicine and has been widely used in China, especially to treat myasthenia gravis (MG). However, the mechanism of...
Conclusions: The results of the network pharmacological analysis indicate that HD mainly acts on EGFR, FOS, ESR1, ESR2, MYC, CASP3, IL-6, and other genes through various active components, such as quercetin, kaempferol, lignan, isorhamnetin, and 7-methoxy-2-methylisoflavone. These components treat myasthenia gravis through anti-inflammatory,...
The role of the gut microbiota and fecal microbiota transplantation in neuroimmune diseases
Source : https://www.frontiersin.org/articles/10.3389/fneur.2023.1108738/full
The gut microbiota plays a key role in the function of the host immune system and neuroimmune diseases. Alterations in the composition of the gut microbiota can lead to pathology...
Posterior reversible encephalopathy syndrome following septicemia in patient with myasthenia gravis
Source : https://www.sciencedirect.com/science/article/pii/S193004332300050X?via=ihub
Posterior reversible encephalopathy syndrome is a clinicoradiologic entity characterized by seizure, headaches, visual symptoms, impaired consciousness, and vasogenic cerebral edema of occipital and parietal lobes of the brain. Magnetic resonance...
Conclusions: Early recognition and management of PRES can reduce morbidity, mortality and may lead to early recovery, especially in patients with septicemia and myasthenia gravis.