Caution on LRP4 antibody results in patients being evaluated for myasthenia gravis
Source : https://www.jni-journal.com/article/S0165-5728(23)00049-8/fulltext
We read with interest the article titled, "LRP4-IgG service line testing in seronegative myasthenia gravis and controls" (Klein et al., 2022). The publication described results of low density lipoprotein receptor-related...
Conclusions/Relevance: Caution is needed in diagnosing myasthenia gravis based on LRP4 antibody positivity alone.
Intravenous immunoglobulin (Gamunex® 10%) is licensed for the treatment of severe acute exacerbations of myasthenia gravis
Source : https://www.tandfonline.com/doi/full/10.1080/14656566.2023.2192867
Dear Editor, In a recent Editorial published in Expert Opinion on Pharmacotherapy, Vanoli and Mantegazza [1] discussed current therapeutics for myasthenia gravis (MG).
Conclusions/Relevance: We believe that it is important for clinicians to have accurate information on the availability of approved therapies. In this case, that IVIg is, in fact, licensed for the treatment of MG exacerbations.
Implementation of tailored exercise programs for MG patients in a gym setting: a pragmatic feasibility case study
Source : https://www.nmd-journal.com/article/S0960-8966(23)00029-9/fulltext
Myasthenia gravis (MG) is an autoimmune disorder where abnormal neuromuscular transmission results in fluctuating skeletal muscle weakness and fatigue, which can be worsened by physical exercise. However, based on several...
Conclusions/Relevance: Our pragmatic open-label case study suggests that well-controlled patients with generalized MG can extend their physical exercise to personal training in the gym. This is an essential step towards reducing the barriers to implementing exercise procols and increasing the availability of these interventions to MG...
Clinicoserological insights into patients with immune checkpoint inhibitor-induced myasthenia gravis - PubMed
Source : https://pubmed.ncbi.nlm.nih.gov/36924454/
The .gov means it's official. Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you're on a federal government site. The site is secure....
Conclusions/Relevance: The contrasting properties of AChR autoantibodies in these cases challenge the accuracy of serological testing in establishing definite ICI-MG diagnoses and underscore the importance of a thorough clinical assessment when evaluating ICI-related adverse events.
Facilities, selection, outcome measurement, and limitations of therapeutic plasma exchange for neuroimmunological disorders: The South East Asian survey study - PubMed
Source : https://pubmed.ncbi.nlm.nih.gov/36896493/
The .gov means it's official. Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you're on a federal government site. The site is secure....
Conclusion: Although countrywise differences exist, all share similarities regarding methods, indications, timing, obstacles, and challenges of TPE for neuroimmunological conditions. Regional collaboration will be essential to identify strategies to reduce these barriers to access to TPE in the future.