Investigation of the Underlying Mechanism of Huangqi-Dangshen for Myasthenia Gravis Treatment via Molecular Docking and Network Pharmacology - PubMed
Source : https://pubmed.ncbi.nlm.nih.gov/36818231/
The herbal pairing of Huangqi and Dangshen (HD) is traditional Chinese herbal medicine and has been widely used in China, especially to treat myasthenia gravis (MG). However, the mechanism of...
Conclusions: The results of the network pharmacological analysis indicate that HD mainly acts on EGFR, FOS, ESR1, ESR2, MYC, CASP3, IL-6, and other genes through various active components, such as quercetin, kaempferol, lignan, isorhamnetin, and 7-methoxy-2-methylisoflavone. These components treat myasthenia gravis through anti-inflammatory,...
The role of the gut microbiota and fecal microbiota transplantation in neuroimmune diseases
Source : https://www.frontiersin.org/articles/10.3389/fneur.2023.1108738/full
The gut microbiota plays a key role in the function of the host immune system and neuroimmune diseases. Alterations in the composition of the gut microbiota can lead to pathology...
Posterior reversible encephalopathy syndrome following septicemia in patient with myasthenia gravis
Source : https://www.sciencedirect.com/science/article/pii/S193004332300050X?via=ihub
Posterior reversible encephalopathy syndrome is a clinicoradiologic entity characterized by seizure, headaches, visual symptoms, impaired consciousness, and vasogenic cerebral edema of occipital and parietal lobes of the brain. Magnetic resonance...
Conclusions: Early recognition and management of PRES can reduce morbidity, mortality and may lead to early recovery, especially in patients with septicemia and myasthenia gravis.
The Usefulness of Swallowing Pressure Assessment in the Identification of Mild Pharyngeal Weakness of Myasthenia Gravis: A Case Report - PubMed
Source : https://pubmed.ncbi.nlm.nih.gov/36824579/
Despite the clinical impact of dysphagia in myasthenia gravis (MG), a standard protocol for diagnosing dysphagia reliably has not yet been established. High-resolution manometry (HRM) provides precise information on pharyngeal...
Conclusions: Swallowing pressure assessment during the EC test may be helpful in identifying mild bulbar symptoms in patients with MG.
COVID-19 and autoimmune diseases of the nervous system - an update - PubMed
Source : https://pubmed.ncbi.nlm.nih.gov/36799522/
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Conclusions: Many reports have indicated that in patients with AIDs, the existence of the disease is not associated with a worse prognosis in the course of the viral infection. Patients in advanced stages of the disease, elderly patients, and those with comorbidities are at risk of more frequent hospitalisations and higher mortality in the...