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Myasthenia Gravis and Five Autoimmune Diseases: a Bidirectional Mendelian Randomization Study

Myasthenia Gravis and Five Autoimmune Diseases: a Bidirectional Mendelian Randomization Study

Source : https://link.springer.com/article/10.1007/s10072-023-07163-3

The association between myasthenia gravis (MG) and other autoimmune diseases is well established. In this study, we aimed to investigate the causal effects between MG and five other autoimmune diseases,...

When MG was treated as the exposure, MR evidence suggested a causal relationship between MG and T1DM, SLE, AITD (both hypothyroidism and hyperthyroidism), and MS (excluding RA).

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Usefulness and Clinical Impact of Whole-Body MRI in Detecting Autoimmune Neuromuscular Disorders

Usefulness and Clinical Impact of Whole-Body MRI in Detecting Autoimmune Neuromuscular Disorders

Source : https://www.mdpi.com/2076-3425/13/10/1500

Autoimmune neuromuscular diseases are a group of heterogenous pathologies secondary to the activation of the immune system that damage the structures of the peripheric nerve, the neuromuscular junction, or the...

The limit of whole-body MRI in assessing myasthenia gravis is its poor spatial resolution for evaluating retroorbital muscles. In this case, the MRI focused on the orbital region is an excellent imaging tool for the evaluation of extraorbital muscle involvement.

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Myasthenia Gravis: Molecular Mechanisms and Promising Therapeutic Strategies

Myasthenia Gravis: Molecular Mechanisms and Promising Therapeutic Strategies

Source : https://www.sciencedirect.com/science/article/abs/pii/S000629522300463X?via=ihub

Myasthenia gravis (MG) is a type of autoimmune disease caused by the blockage of neuromuscular junction transmission.

The treatment of MG has changed from traditional drug therapies, such as AChEI and corticosteroids, to novel therapies using biologicals, such as B- and T-cell targeted immunotherapies, complement inhibitor therapy, FcRn inhibitor therapy, and stem cell therapy.

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Myasthenia Gravis as Initial Presentation of a Pancreatic Neuroendocrine Tumor: a Case Report

Myasthenia Gravis as Initial Presentation of a Pancreatic Neuroendocrine Tumor: a Case Report

Source : https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10580239/

Myasthenia gravis (MG) is a heterogeneous autoimmune disease, which is characterized by a postsynaptic neuromuscular transmission defect.

Because the efficient treatment of neuroendocrine neoplasia (NEN) is instrumental in achieving a complete remission of myasthenia gravis, screening for rare neuroendocrine malignancies, including pancreatic NEN, could be considered in the diagnostic evaluation.

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Coverage of the American Association of Neuromuscular & Electrodiagnostic Medicine (AANEM) 2023 Annual Meeting

The annual meeting of the American Association of Neuromuscular & Electrodiagnostic Medicine (AANEM) brings together neurologists, physiatrists, researchers, and advanced practice providers to learn more about the latest advancements in neuromuscular disorders and musculoskeletal and electrodiagnostic medicine. The four-day meeting is taking place at the JW Marriott Phoenix Desert Ridge Resort & Spa.

Thanks to the advent of targeted therapies and improved diagnosis, myasthenia gravis, a chronic autoimmune neuromuscular disorder, took center stage during many presentations and symposia at this year’s meeting.

Click above for a summary of presentations that caught our eye at the conference.