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Myasthenia gravis following the initiation of statin therapy: A multinational self-controlled case series study - PubMed

Myasthenia gravis following the initiation of statin therapy: A multinational self-controlled case series study - PubMed

Source : https://pubmed.ncbi.nlm.nih.gov/41645666/

In this multinational SCCS study, statin initiation may be associated with increased risk of new-onset MG during the first 6-12 months, with greater magnitude of risk elevation for higher intensity...

Multinational self-controlled case series shows increased risk of new-onset myasthenia gravis within 6–12 months of statin initiation, particularly early and with higher-intensity statin therapy, using real-world population data.

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Did you know? Precision neurology is transforming care by integrating genomics, biomarkers, advanced imaging, and computational modeling to tailor diagnosis and treatment at the individual level. By moving beyond population averages, this approach enables earlier detection, better trial stratification, and more personalized therapeutic decisions across conditions like Alzheimer’s, Parkinson’s, epilepsy, and stroke.

How might integrating multi-omics and brain imaging reshape personalized decision-making in everyday neurological practice?

NCCN Guidelines

How might integrating multi-omics and brain imaging reshape personalized decision-making in everyday neurological practice?

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Wearable sensors enable non-invasive, continuous assessment of motor, autonomic, and cognitive function in children with neurological disorders. By capturing real-world data, they address limitations of subjective scales and support earlier detection of disease progression and treatment response.

Explore emerging digital neurology tools

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Serum from patients with acetylcholine receptor antibody-positive myasthenia gravis triggers pathogenic changes in human myotube cells - PubMed

Serum from patients with acetylcholine receptor antibody-positive myasthenia gravis triggers pathogenic changes in human myotube cells - PubMed

Source : https://pubmed.ncbi.nlm.nih.gov/41621163/

Factors other than acetylcholine signal transmission inhibition may contribute to the pathogenesis of AChR antibody-positive MG. Further research is needed to clarify the pathways involved, potentially leading to more tailored...

Patient serum from AChR-positive generalized myasthenia gravis induces transcriptomic, structural, and functional abnormalities in human myotubes, supporting pathogenic mechanisms beyond neuromuscular transmission blockade and informing development of targeted immunomodulatory therapies.