micro-community-banner
 
  • Saved

3w
Post-hoc analyses from the ADAPT clinical study demonstrate aggregate sustained benefit of Efgartigimod in generalized myasthenia gravis - PubMed

Post-hoc analyses from the ADAPT clinical study demonstrate aggregate sustained benefit of Efgartigimod in generalized myasthenia gravis - PubMed

Source : https://pubmed.ncbi.nlm.nih.gov/39426360/

The clinical benefit of efgartigimod was sustained over repeat treatment cycles and maintained over the long term. Response to treatment was consistent regardless of response definition and was repeated in...

Post-hoc analyses of ADAPT and ADAPT+ trials show sustained, robust, and repeatable clinical benefits of efgartigimod in AChR-Ab+ generalized myasthenia gravis, with consistent response rates across definitions, disease duration, and prior therapy exposure.

  • Saved

3w
American Association of Neuromuscular & Electrodiagnostic Medicine Summary

The 2025 annual meeting of the American Association of Neuromuscular & Electrodiagnostic Medicine (AANEM) took place in San Francisco from Oct. 29 to Nov. 1, 2025. Spanning four days, the meeting brought together physicians, technologists, advanced practice providers, and other health care professionals to learn more about the latest advances in neuromuscular medicine, electrodiagnostic medicine, and neuromuscular ultrasound, including the rapidly evolving landscape for treating myasthenia gravis. 

Click above for an exclusive summary of this year's conference!

  • Saved

3w
case study

Patient Background:

A 23-year-old woman with childhood-onset Moyamoya disease presented with recurrent seizures and a history of cerebrovascular events. At age 5, she experienced focal motor seizures, initially misattributed to psychogenic causes. By age 7, she developed acute right-sided weakness and aphasia, resulting in residual facial palsy and partial aphasia.

By 2023, exam findings included asthenic habitus, venous insufficiency, mild cognitive impairment (MMSE 26), hyperreflexia (right > left), distal right arm weakness, prosopagnosia, and severe myopia.

Assessment & Diagnosis:

An MRI from 2005 revealed right hemisphere atrophy. In 2006, cerebral angiography confirmed Moyamoya disease, with bilateral carotid artery occlusions and collateral “puff of smoke” vessels. Repeat MRI in 2023 demonstrated chronic ischemic lesions, and angiography confirmed diminished anterior circulation with compensatory collaterals. EEG revealed right-sided background slowing and left temporoparietal epileptiform discharges, consistent with focal seizures. Neuropsychological testing showed mild cognitive disorder with visual–spatial deficits and agnosia.

  1. How is seizure control balanced with stroke prevention in Moyamoya disease?
  2. When is revascularization considered in Moyamoya with seizures, and how is perioperative seizure risk managed?
  • Saved

4w
Mental Health Experiences and Challenges Among Individuals with Myasthenia Gravis: Insights from Patient-Centered, Qualitative Analyses - PubMed

Mental Health Experiences and Challenges Among Individuals with Myasthenia Gravis: Insights from Patient-Centered, Qualitative Analyses - PubMed

Source : https://pubmed.ncbi.nlm.nih.gov/41123841/

This qualitative, hypothesis-generating study found that individuals with MG in the US were more likely to report experiencing anxiety and depression than the general population due, at least in part,...

This qualitative study highlights high rates of anxiety and depression in myasthenia gravis, identifying stressors linked to symptom burden, care demands, and social challenges that exacerbate psychological distress throughout the disease journey.

  • Saved

1mo
American Association of Neuromuscular & Electrodiagnostic Medicine Annual Meeting

The 2025 annual meeting of the American Association of Neuromuscular & Electrodiagnostic Medicine (AANEM) spans four days and is taking place in San Francisco, along with an option to participate virtually. The meeting brings physicians, technologists, advanced practice providers, and other health care professionals together to learn about the latest advances in neuromuscular medicine, electrodiagnostic medicine, neuromuscular ultrasound, and more, with presentations and posters covering the influx of new therapies and technologies.

Click above to access a full summary of sessions so far.