Nutraceuticals and migraine: further strategy for the treatment of specific conditions - Neurological Sciences
Source : https://link.springer.com/article/10.1007/s10072-022-06250-1
Nutraceuticals might be defined as food or dietary supplements that provide medicinal or health benefits. Current preventive treatment of migraine includes nutraceuticals as well as conventional drugs.
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Huma Sheikh, CEO, NY Neurology Medicine, PC3yrTHere is now more and more evidence for these now.
The importance of an early onset of migraine prevention: an evidence-based, hypothesis-driven scoping literature review - PubMed
Source : https://pubmed.ncbi.nlm.nih.gov/35662957/
Recently approved migraine preventive therapies facilitate rapid control of migraine activity, potentially improving patients' lives and minimizing the societal burden of migraine. This review synthesizes available evidence on rates and...
Relevance: Recently approved migraine preventive therapies facilitate rapid control of migraine activity, potentially improving patients' lives and minimizing the societal burden of migraine. This review synthesizes available evidence on rates and timing of early onset of migraine prevention and identifies patient-level outcomes related to...
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Huma Sheikh, CEO, NY Neurology Medicine, PC3yrEarly diagnosis and treatment of migraine is so essential.
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Migraine Connect3yrKey Points • Source: Therapeutic Advances in Neurological Disorders • Conclusion: “No evidence was identified in any publication to support the null hypothesis that patients with migraine do not benefit from an early onset Show More
Patient characteristics and treatment utilization among patients with migraine initiating self-injectable calcitonin gene-related peptide monoclonal antibody and novel acute medication
Source : https://www.tandfonline.com/doi/abs/10.1080/03007995.2022.2091333?journalCode=icmo20
Abstract This study described patient characteristics and utilization of recently approved novel acute medication and calcitonin gene-related peptide (CGRP) monoclonal antibodies. This retrospective observational study utilized the IBM MarketScan Research...
Conclusions: Understanding patient characteristics and treatment utilization patterns among patients prescribed both a CGRP mAb and novel acute medication may provide valuable insight regarding migraine treatment selection for healthcare decision makers.
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Huma Sheikh, CEO, NY Neurology Medicine, PC3yrThis should be available to everyone.
Pharmacokinetics and Safety of Erenumab after a Single Subcutaneous Injection Dose in Healthy Chinese Subjects - PubMed
Source : https://pubmed.ncbi.nlm.nih.gov/35727536/
doi: 10.1007/s40261-022-01171-5. Online ahead of print. 1 Clinical Trial Center/NMPA Key Laboratory for Clinical Research and Evaluation of Innovative Drug, West China Hospital of Sichuan University, No.5 Telecom Road, Wuhou...
Conclusions: Erenumab was safe and well tolerated after a single subcutaneous injection in healthy Chinese subjects. The systemic exposure in Chinese subjects in terms of AUC0-∞ was 70% higher than that in White subjects as previously reported.
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Huma Sheikh, CEO, NY Neurology Medicine, PC3yrThis is good real world data.
Conversion from chronic to episodic migraine in patients treated with galcanezumab in real life in Italy: the 12-month observational, longitudinal, cohort multicenter GARLIT experience - Journal of Neurology
Source : https://link.springer.com/article/10.1007/s00415-022-11226-4
Objective To investigate in real-life the conversion from chronic migraine (CM) to episodic migraine (EM), specifically to EM with High-Frequency (HFEM: 8-14 monthly migraine days, MMDs), Medium-Frequency (MFEM, 4-7 MMDs),...
Discussion: The 1-year GARLIT experience suggests that more than half of CM patients treated with galcanezumab persistently reverted to EM in real life.
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Huma Sheikh, CEO, NY Neurology Medicine, PC3yrGreat study.