Intracerebral haemorrhage in multiple sclerosis: assessing the impact of disease-modifying medications
Source : https://pubmed.ncbi.nlm.nih.gov/38918831/
Multiple Sclerosis (MS) is a complex autoimmune disorder that significantly impacts the central nervous system, leading to a range of complications. While intracranial haemorrhage (ICH) is a rare but highly...
MS management is challenged by the risk of ICH, influenced by DMDs like Dimethyl Fumarate and Fingolimod, requiring personalized strategies considering patient-specific factors and ongoing research.
Human Umbilical Cord-Derived Mesenchymal Stem Cells in the Treatment of Multiple Sclerosis Patients: Phase I/II Dose-Finding Clinical Study
Source : https://pubmed.ncbi.nlm.nih.gov/38450623/
Multiple sclerosis (MS) is a chronic neuro-inflammatory disease resulting in disabilities that negatively impact patients' life quality. While current treatment options do not reverse the course of the disease, treatment...
A study demonstrated the safety and potential efficacy of two UC-MSC treatment protocols in MS patients, with better outcomes observed in the two-dose group.
Headache in Multiple Sclerosis: A Narrative Review
Source : https://pubmed.ncbi.nlm.nih.gov/38674218/
Background : Multiple sclerosis (MS) is a chronic inflammatory demyelinating disorder of the central nervous system characterized by autoimmune-mediated damage to oligodendrocytes and subsequent myelin destruction. Clinical implications : Clinically,...
Headache, common in MS patients, often signals early disease and can be exacerbated by some therapies. Understanding this link aids in better patient management and treatment decisions.
Understanding multiple sclerosis as a disease spectrum: above and below the clinical threshold
Source : https://pubmed.ncbi.nlm.nih.gov/38535979/
Aligning on a consistently-applied mechanistic framework at distinct levels of explanation will enable greater precision across bench and clinical research, and inform discourse on drivers of disability progression and delivery...
Adopting a unified mechanistic framework for MS will enhance precision in research, prognostication, and treatment, bridging gaps between pathobiology and clinical outcomes.
Artificial Intelligence and Multiple Sclerosis
Source : https://pubmed.ncbi.nlm.nih.gov/38940994/
In this paper, we analyse the different advances in artificial intelligence (AI) approaches in multiple sclerosis (MS). AI applications in MS range across investigation of disease pathogenesis, diagnosis, treatment, and...
AI promises significant advancements in MS management, enhancing diagnosis, prognosis, and treatment personalization. Ensuring model interpretability and transparency will be crucial for clinical integration.