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Paraneoplastic Myasthenia Gravis Due to Ovarian Cancer - Indian Journal of Pediatrics

Paraneoplastic Myasthenia Gravis Due to Ovarian Cancer - Indian Journal of Pediatrics

Source : https://link.springer.com/article/10.1007/s12098-023-04550-8

Department of Pediatrics, Okinawa Prefectural Nanbu Medical Center and Children's Medical Center, 118-1, Shinkawa, Haebaru-cho, Shimajiri-gun, Okinawa, 901-1193, Japan Tomonori Kurimoto, Tsuyoshi Matsuoka, Takehiro Matsuda, Takeshi Yagi, Itsuki Inamine &...

Conclusions/Relevance: When MG is suspected, PNS is also possible, and in children it is necessary to investigate tumors other than thymoma.

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Long-term home mechanical ventilation using a noninvasive ventilator via tracheotomy in patients with myasthenia gravis: a case report and literature review - PubMed

Long-term home mechanical ventilation using a noninvasive ventilator via tracheotomy in patients with myasthenia gravis: a case report and literature review - PubMed

Source : https://pubmed.ncbi.nlm.nih.gov/37073798/

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Conclusion: In patients requiring HMV, selection of NIV or IMV should be individualized. Tracheostomy preservation should be considered in some patients with advanced NMD if there is respiratory muscle weakness or the risk of aspiration. And attempts can be made to use a noninvasive ventilator because of its advantages of portability, ease of...

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Oxymetazoline Hydrochloride Eye-Drops as Treatment for Myasthenia Gravis-Related Ptosis: A Description of Two Cases

Oxymetazoline Hydrochloride Eye-Drops as Treatment for Myasthenia Gravis-Related Ptosis: A Description of Two Cases

Source : https://www.cureus.com/articles/140781-oxymetazoline-hydrochloride-eye-drops-as-treatment-for-myasthenia-gravis-related-ptosis-a-description-of-two-cases

In this article, we described two patients with myasthenia gravis-related ptosis who experienced sustained improvement with the use of oxymetazoline hydrochloride ophthalmic solution 0.1%. Despite the commonly used treatments for...

Conclusion/Relevance: Our case report suggests the long-term efficacy of daily use of oxymetazoline eye drops in improving ptosis, providing a potential alternative or adjunctive treatment option without significant adverse effects. Further research is necessary to confirm these observations across larger cohorts of MG patients and establish...

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Immune checkpoint inhibitor sintilimab-induced lethal... : Medicine

Immune checkpoint inhibitor sintilimab-induced lethal... : Medicine

Source : https://journals.lww.com/md-journal/Fulltext/2023/04140/Immune_checkpoint_inhibitor_sintilimab_induced.30.aspx

al, have been increasing reported. Patient concerns: A 45-year-old thymoma patient was admitted to our hospital after receiving anti-programmed cell death-1 treatment with sintilimab 14 days later, accompanied by abdominal...

Lessons: The case aims to raise awareness of immune-mediated cardiotoxicity and bring thoughts to the prospects of immunotherapy in thymoma.

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Transcriptional landscape of myasthenia gravis revealed by weighted gene coexpression network analysis

Transcriptional landscape of myasthenia gravis revealed by weighted gene coexpression network analysis

Source : https://www.frontiersin.org/articles/10.3389/fgene.2023.1106359/full

Background: As one of the most common autoimmune diseases, myasthenia gravis (MG) severely affects the quality of life of patients.

Conclusion: In this study, a diagnostic model based on the co-expression module of MG dysregulated genes was constructed, which has good diagnostic performance and contributes to the diagnosis of MG.