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Comparing the Impact of COVID-19 on Vaccinated and Unvaccinated Patients Affected by Myasthenia Gravis - PubMed

Comparing the Impact of COVID-19 on Vaccinated and Unvaccinated Patients Affected by Myasthenia Gravis - PubMed

Source : https://pubmed.ncbi.nlm.nih.gov/37109594/

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Conclusions: International and Italian guidelines have considered MG patients to be frail and prioritized their vaccination, as well as the vaccination of other patients affected by autoimmune diseases such as Multiple Sclerosis. Our data further support this view. The impact of SARS-CoV-2 infection was indeed considerably more negative in...

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2yr
Myasthenia gravis, respiratory function, and respiratory tract disease - PubMed

Myasthenia gravis, respiratory function, and respiratory tract disease - PubMed

Source : https://pubmed.ncbi.nlm.nih.gov/37101094/

Myasthenia gravis (MG) is characterized by muscle weakness caused by autoantibodies that bind to the postsynaptic membrane at the neuromuscular junction and impair acetylcholine receptor function. Weakness of respiratory muscles...

Conclusions/Relevance: MG patients with respiratory muscle weakness need active immunosuppressive drug treatment long term, and they need regular specialist follow-up. Comorbidities affecting respiratory function need attention and optimal treatment. Respiratory tract infections can lead to MG exacerbations and precipitate an MG crisis....

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Post-Conference Summary of the American Academy of Neurology: AAN 2023 Annual Meeting

The 75th American Academy of Neurology (AAN) Annual Meeting took Boston by storm.

The six-day meeting, which was held at the Boston Convention and Exhibition Center from April 22 to 27, 2023, featured presentations, keynote lectures, abstracts, and posters on the latest advances in the diagnosis and treatment of a full spectrum of neurologic conditions, from epilepsy and stroke to migraine and movement disorders.

Click above for our post-conference wrap-up report.

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Outcomes of COVID-19 Infection and Vaccination Among Individuals With Myasthenia Gravis - PubMed

Outcomes of COVID-19 Infection and Vaccination Among Individuals With Myasthenia Gravis - PubMed

Source : https://pubmed.ncbi.nlm.nih.gov/37097637/

This study suggests that adults with MG who contracted COVID-19 had a higher risk of hospitalization and death compared with matched controls. Vaccine uptake was high, with negligible risk of...

Meaning: This population-based study suggests that patients with myasthenia gravis had a high risk of serious COVID-19 infection and worse outcomes compared with the general population, supporting the prioritization of this population for vaccination and early therapeutics for COVID-19.

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2yr
Efgartigimod Alfa

Efgartigimod Alfa

Source : https://www.ncbi.nlm.nih.gov/books/NBK588128/

No information is available on the clinical use of efgartigimod alfa during breastfeeding. Because efgartigimod alfa is a large protein molecule with a molecular weight of 54,000 Da, the amount...

Summary of Use During Lactation: No information is available on the clinical use of efgartigimod alfa during breastfeeding. Because efgartigimod alfa is a large protein molecule with a molecular weight of 54,000 Da, the amount in milk is likely to be very low. It is also likely to be partially destroyed in the infant's gastrointestinal tract...