Ravulizumab: A Review in Generalised Myasthenia Gravis - Drugs
Source : https://link.springer.com/article/10.1007/s40265-023-01877-6
Ravulizumab (ULTOMIRIS®) is the first long-acting complement C5 inhibitor (administered intravenously every 8 weeks) to be approved in several countries globally, for adults with generalised myasthenia gravis (gMG) who are...
Conclusions/Relevance: Ravulizumab is an efficacious, generally well tolerated and convenient treatment option in adults with AChR Ab+ gMG, expanding the options available for gMG management.ravulizumab is an efficacious, generally well tolerated and convenient treatment option in adults with AChR Ab+ gMG, expanding the options available for...
Patient-reported impact of myasthenia gravis in the real world: findings from a digital observational survey-based study (MyRealWorld MG)
Source : https://bmjopen.bmj.com/content/13/5/e068104
Objectives This study aims to explore the impact of myasthenia gravis (MG) - in terms of treatments, side effects, comorbidities, psychological health and work or study- in the real world...
Conclusions: This analysis of baseline characteristics of the MyRealWorld MG study population indicates that, despite current treatments, patients experience notable burden. Further scheduled analyses will develop a longitudinal picture of MG burden.
Concordance between patient- and physician-reported Myasthenia Gravis Activities of Daily Living (MG-ADL) scores - PubMed
Source : https://pubmed.ncbi.nlm.nih.gov/37144893/
The .gov means it's official. Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you're on a federal government site. The site is secure....
Discussion: Our results demonstrate that patients and neurologists have a concordant assessment of the patient's MG symptoms when using the MG-ADL scale. This evidence supports patient self-administration of the MG-ADL in clinical practice and research.
Type 2 diabetes mellitus as a possible risk factor for myasthenia gravis: a case-control study
Source : https://www.frontiersin.org/articles/10.3389/fneur.2023.1125842/full
BackgroundA certain number of myasthenia gravis (MG) patients clinically had type 2 diabetes mellitus (T2DM) prior to MG onset, which suggests that the onset of MG may correlate with the...
Interpretation: This study demonstrates that T2DM is strongly associated with the subsequent risk of MG and varies significantly by sex and age. It reveals that diabetic MG may be a unique subtype that is different from the conventional MG subgroup classification. More clinical and immunological features of diabetic MG patients need to...
Comparing the Impact of COVID-19 on Vaccinated and Unvaccinated Patients Affected by Myasthenia Gravis - PubMed
Source : https://pubmed.ncbi.nlm.nih.gov/37109594/
The .gov means it's official. Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you're on a federal government site. The site is secure....
Conclusions: International and Italian guidelines have considered MG patients to be frail and prioritized their vaccination, as well as the vaccination of other patients affected by autoimmune diseases such as Multiple Sclerosis. Our data further support this view. The impact of SARS-CoV-2 infection was indeed considerably more negative in...