A rare association: Obesity hypoventilation syndrome with myasthenia gravis and systemic lupus erythematosus, case report
Source : https://www.sciencedirect.com/science/article/pii/S2213007123000436?via=ihub
Author links open overlay panel Safwat Eldaabossi a b , , , , , , , , , , , , , Show more Shrinking lung syndrome (SLS) is an...
Conclusion: The interesting aspect of this case report: is the presentation of the overlap of obesity hypoventilation syndrome and shrinking lung syndrome due to systemic lupus erythematosus with generalized and respiratory muscle dysfunction due to myasthenia gravis with good outcomes after therapy.
Clinical and immune-related factors associated with exacerbation in adults with well-controlled generalized myasthenia gravis
Source : https://www.frontiersin.org/articles/10.3389/fimmu.2023.1177249/full
ObjectivesTo describe the clinical predictors and immune-related factors for exacerbation in adults with well-controlled generalized myasthenia gravis (GMG).MethodsWe conducted a retrospective analysis of 585 adults with well-controlled GMG from our...
Conclusion: Myasthenia gravis (MG) exacerbations were more frequent in those patients with older onset age, longer disease duration, more severe MGFA classification, positive AChR-ab, and lack of combined immunotherapy or thymectomy treatment. On the other hand, CD3–CD19+ B cells, CD3+CD8+ T cells, Tregs, and AChR-ab in peripheral blood may...
Safety of COVID-19 vaccine in patients with myasthenia gravis: a self-controlled case series study
Source : https://www.frontiersin.org/articles/10.3389/fimmu.2023.1141983/full
BackgroundThe safety of COVID-19 vaccines has been clarified in clinical trials; however, some immunocompromised patients, such as myasthenia gravis (MG) patients, are still hesitant to receive vaccines. Whether COVID-19 vaccination...
Conclusion: COVID-19 vaccination has no long-term impact on MG relapse.
Circulating CXCR5+ natural killer cells are expanded in patients with myasthenia gravis - PubMed
Source : https://pubmed.ncbi.nlm.nih.gov/37223338/
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Conclusion: These results reveal that CXCR5+ NK cells exhibit distinct phenotypes and functions compared with CXCR5− NK cells and might participate in the pathogenesis of MG.
Fungal Gut Microbiome in Myasthenia Gravis: A Sub-Analysis of the MYBIOM Study - PubMed
Source : https://pubmed.ncbi.nlm.nih.gov/37233280/
An altered gut microbiota is a possible contributing pathogenic factor in myasthenia gravis (MG), an autoimmune neuromuscular disease. However, the significance of the fungal microbiome is an understudied and neglected...
Conclusions/Relevance: Besides one MG patient with abundant Ca. albicans, no prominent dysbiosis in the MG group of the mycobiome was found. Not all fungal sequences within all groups were successfully assigned, so further sub-analysis was withdrawn, limiting robust conclusions.