Dropped Head Syndrome As a Presenting Sign of Different Diseases: Report of Three Cases - PubMed
Source : https://pubmed.ncbi.nlm.nih.gov/37287555/
Dropped head is an abnormal forward flexion of the cervical spine. Patients can straighten their heads with support. This condition, which is seen as neck extensor muscle weakness, is defined...
Relevance: We aimed to present 3 different cases with a diagnosis of myasthenia gravis, inflammatory myopathy, and amyotrophic lateral sclerosis presenting with dropped head.
New-Onset Myasthenia Gravis Mimics Spinal Cord Injury After Zenker's Diverticulum Repair - PubMed
Source : https://pubmed.ncbi.nlm.nih.gov/37305099/
New-Onset Myasthenia Gravis Mimics Spinal Cord Injury After Zenker's Diverticulum Repair
Conclusions/Relevance: This report presents a rare case of new-onset MG diagnosed in the immediate postoperative period after a Zenker's repair. It demonstrates that intraoperative events can unmask MG during the subclinical stage of the disease, lead physicians to other diagnostic considerations because of the general unfamiliarity with this...
When Breathing Becomes a Challenge: A Case of Congenital Myasthenia Gravis in an Indian Neonate With a DOK-7 Gene Mutation
A rare neuromuscular condition known as congenital myasthenia gravis (CMG) affects some people from birth or very soon after. It results in fatigue and muscle weakness because of genetic abnormalities...
Relevance: A newborn with CMG due to a DOK-7 gene mutation is described in this article, along with its very early onset. The DOK-7 mutation is a rare variant in the Indian population that causes CMG and usually manifests as 'limb girdle' weakness. However, due to muscle weakness, the neonate in this case developed severe respiratory distress...
The impact of thymectomy in subgroups of Myasthenia gravis patients: a single center longitudinal observation - Neurological Research and Practice
Source : https://neurolrespract.biomedcentral.com/articles/10.1186/s42466-023-00252-w
Background Myasthenia gravis (MG) is a rare neuromuscular disorder. Symptoms can range from ptosis only to life threatening myasthenic crisis. Thymectomy is recommended for anti-acetylcholine receptor-antibody positive patients with early-onset...
Conclusion: Our study confirms the benefit of thymectomy in the therapy of MG. Both, the concentration of acetylcholine receptor antibodies and the necessary dosage of cortisone therapy show a continuous regression after thymectomy in the overall cohort. Beyond EOMG, groups of LOMG and thymomatous MG responded to thymectomy as well, but...
Mogamulizumab-Associated Myositis With and Without Myasthenia Gravis and/or Myocarditis in Patients With T-Cell Lymphoma - PubMed
Source : https://pubmed.ncbi.nlm.nih.gov/37285523/
Mogamulizumab is being increasingly prescribed for the treatment of T-cell lymphomas (MF/SS/ATLL). We conducted a retrospective cohort study to identify muscular immune-related adverse events (irAEs) associated with mogamulizumab in patients...
Conclusions/Relevance: We highlight the utility of IVIG, together with systemic corticosteroids, for the treatment of these potentially fatal side effects associated with mogamulizumab therapy.