A Case of Anti-Acetylcholine Receptor Antibody-Positive Ocular Myasthenia Gravis With Anti-Titin Antibody and Anti-Kv1.4 Antibody Positive Inflammatory Myopathy
Source : https://pubmed.ncbi.nlm.nih.gov/37989286/
An 84-year-old man was diagnosed with anti-acetylcholine receptor (AChR) antibody-positive ocular myasthenia gravis (OMG) at the age of 77 and received treatment. The patient was referred to our department with...
Evaluation of disease activity with serum anti-AChR antibody levels, and assessment of prognosis with examining antistriational antibodies are necessary for appropriate management of IM associated with MG.
Comorbidity of Myasthenia Gravis and Graves' Disease as Immune Reconstitution-Associated Autoimmune Disease in HIV Infection: a Case Report and Literature Review
Source : https://pubmed.ncbi.nlm.nih.gov/37990629/
This is a rare case of HIV-related immune reconstitution-associated autoimmune disease (IRAD) with comorbidity of MG and GD which was reported initially. Cooperation with multidisciplinary teams is essential to avoid...
Little study has been done on the link between HIV-related immune reconstitution and autoimmune diseases occurring after antiretroviral therapy.
Erythroderma Combined With Deeper Dermal Dermatophytosis Due to Trichophyton Rubrum in a Patient With Myasthenia Gravis: First Case Report and Literature Review
Source : https://bmcinfectdis.biomedcentral.com/articles/10.1186/s12879-023-08752-5
Dermatophytes are the most common causative pathogens of mycoses worldwide and usually cause superficial infections. However, they can enter deep into the dermis lead to invasive dermatophytosis such as deeper...
Management strategies for patients with thymoma with myasthenia gravis, especially long-term use of immunosuppressive agents, will inevitably lead to immune disorders causing severe infectious diseases.
TLR4-MyD88-NF-κB Signaling Imbalances Th17 and Treg Cells in Thymoma With Myasthenia Gravis
Source : https://pubmed.ncbi.nlm.nih.gov/37975358/
TLR4 is stimulated in thymoma, causing an increase of Th17 cells and a decrease of Treg cells, namely an imbalance of Th17/Treg cells, resulting in MG.
TLR4, MyD88, and NF-κB were expressed more in MG thymoma compared with simple thymoma.
Causal Relationship Between Gut Microbiota and Myasthenia Gravis: a Bidirectional Mendelian Randomization Study
Source : https://cellandbioscience.biomedcentral.com/articles/10.1186/s13578-023-01163-8
Observational studies have demonstrated an association between gut microbiota and myasthenia gravis; however, the causal relationship between the two still lacks clarity. Our goals are to ascertain the existence of...
The results demonstrated that the families Clostridiaceae, Defluviitaleaceae, and Enterobacteriaceae were negatively correlated with risk of MG, whereas the genus Lachnoclostridium was positively correlated with risk of MG.