Oral methadone and buprenorphine remain gold standards for OUD. New depot buprenorphine, retarded morphine, and diacetylmorphine offer alternatives, especially for refractory patients. Depot options improve adherence, supporting tailored, long-term management.
The Immunoglobulin National Society (IgNS) will hold its 14th National Conference from Oct. 16 to 19 in Dallas. The conference is the premier annual event for clinicians, business professionals, and industry leaders in the immunoglobulin (Ig) therapy and biologics space. Attendees will learn about the latest advancements in patient care and make connections with colleagues.
Click to access highlights that are in the upcoming conference.
Source : https://pubmed.ncbi.nlm.nih.gov/41042847/
Biological tissues exhibit sharp phase transitions where cells collectively transition from disordered to ordered states at critical densities. We demonstrate through bio-chemo-mechanical modeling that this emergent behavior arises from a...
This study models how extracellular matrix stiffness regulates collective cell polarization and tissue remodeling, revealing critical spacing thresholds that govern cell–cell mechanical communication—offering mechanobiological insights relevant to fibrosis and neuromuscular repair.
Source : https://pubmed.ncbi.nlm.nih.gov/40995903/
The majority of patients with OMG develop generalized disease within the first two years. Major risk factors for generalization include female sex, elevated AChR antibody titers, and abnormal findings on...
Retrospective cohort of ocular myasthenia gravis patients found 65.6% progressed to generalized MG, mostly within two years; age, sex, antibody status, and thymoma were key predictors of disease generalization.