Impact of the COVID-19 Pandemic on People Living With Rare Diseases and Their Families: Results of a National Survey
Source : https://pubmed.ncbi.nlm.nih.gov/38354030/
Self-reported COVID-19 was more frequent than expected and was associated with increased prevalence and severity of RD symptoms and greater use of medications. The pandemic negatively affected access to care...
The racial and ethnic profile of the respondents living with myasthenia gravis was similar to that of the participants of a national registry, but it is possible that the registry also underrepresented minority groups.
Defective Autophagy and Autophagy Activators in Myasthenia Gravis: a Rare Entity and Unusual Scenario
Source : https://pubmed.ncbi.nlm.nih.gov/38346408/
Myasthenia gravis (MG) is an autoimmune disease of the neuromuscular junction (NMJ) that results from autoantibodies against nicotinic acetylcholine receptors (nAchRs) at NMJs. These autoantibodies are mainly originated from autoreactive...
As autophagy is involved in autoimmune disorders, it may play a major role in the pathogenesis of MG.
Are the Minimally Invasive Techniques the New Gold Standard in Thymus Surgery for Myasthenia Gravis? Experience of a Reference Single-Site in VATS Thymectomy
Source : https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10867208/
The thymus is the primary lymphoid organ responsible for the maturation and proliferation of T lymphocytes. During the first years of our lives, the activation and inactivation of T lymphocytes...
The authors aimed to analyze the impact of robotic-assisted thoracoscopic thymectomy on symptoms and corticosteroid dosage in patients with MG, identifying factors that may predict a better response to surgery.
Therapeutic Effect and Side Effects of Pharmacotherapy in Patients With Parkinson Disease and Myasthenia Gravis: a Systematic Review of Case Reports and Case Series Studies
Source : https://pubmed.ncbi.nlm.nih.gov/38360447/
When treating a patient who has PD or MG, health providers should be cautious about the occurrence of another disease. Timely treatment must rely on monitoring new symptoms as soon...
When treating a patient who has Parkinson disease or myasthenia gravis, HCPs should be cautious about the occurrence of another disease.
Mendelian Randomization Study Revealed a Gut Microbiota-Neuromuscular Junction Axis in Myasthenia Gravis
Source : https://www.nature.com/articles/s41598-024-52469-7
A growing number of studies have implicated that gut microbiota abundance is associated with myasthenia gravis (MG). However, the causal relationship underlying the associations is still unclear. Here, we aim...
Genetic evidence identified causal associations between gut microbiota and myasthenia gravis (MG), thus suggesting novel insights into the microbiota-neuromuscular junction axis in the pathogenesis of MG.