Treating myasthenia gravis beyond the eye clinic - PubMed
Source : https://pubmed.ncbi.nlm.nih.gov/38789789/
Myasthenia gravis (MG) is one of the most well characterised autoimmune disorders affecting the neuromuscular junction with autoantibodies targeting the acetylcholine receptor (AChR) complex. The vast majority of patients present...
Myasthenia gravis is an autoimmune disorder affecting neuromuscular junctions, causing muscle weakness, often starting with ocular symptoms. Management includes cholinesterase inhibitors, immunosuppressants, and evolving therapies targeting immune components.
Does Surgical Removal of the Thymus Have Deleterious Consequences?
Source : https://pubmed.ncbi.nlm.nih.gov/38781559/
The role of immunosenescence, particularly the natural process of thymic involution during aging, is increasingly acknowledged as a factor contributing to the development of autoimmune diseases and cancer. Recently, a...
Thymectomy benefits in MG and thymoma patients outweigh long-term cancer and autoimmunity risks, but incidental thymic removal during other surgeries should be minimized.
Thymoma-associated autoimmune encephalitis with myasthenia gravis: Case series and literature review
Source : https://pubmed.ncbi.nlm.nih.gov/38421083/
There was no significant difference in the clinical manifestations between these patients and others with only TAMG or TAAE. TAAE was commonly associated with AMPAR2-Ab. Significantly, AE more commonly heralded...
Thymoma-associated autoimmune encephalitis (TAAE) commonly signals thymoma recurrence and is associated with AMPAR2 antibodies. Autoimmune encephalitis onset is a more frequent indicator of recurrence than myasthenia gravis onset.
Efgartigimod-associated Kaposi's varicelliform eruption and herpetic conjunctivitis in a patient with seropositive ocular myasthenia gravis: a case report and review
Source : https://pubmed.ncbi.nlm.nih.gov/39148733/
This case is the first report of a patient with KVE and herpetic conjunctivitis related to efgartigimod in PubMed. This is rare and unusual. Clinicians should be alert to the...
A 60-year-old man with ocular myasthenia gravis developed Kaposi's varicelliform eruption and herpetic conjunctivitis after efgartigimod treatment, highlighting rare complications requiring clinician awareness.
Does Surgical Removal of the Thymus Have Deleterious Consequences
Source : https://pubmed.ncbi.nlm.nih.gov/38781559/
The role of immunosenescence, particularly the natural process of thymic involution during aging, is increasingly acknowledged as a factor contributing to the development of autoimmune diseases and cancer. Recently, a...
Thymectomy benefits patients with MG and thymoma, outweighing risks of cancer and autoimmunity, but incidental thymus removal during other surgeries should be minimized to avoid potential long-term consequences.