Improvement of fatigue in generalised myasthenia gravis with zilucoplan
Source : https://pubmed.ncbi.nlm.nih.gov/38400914/
Treatment with zilucoplan demonstrated statistical and clinically meaningful improvements in fatigue scores and severity versus placebo during RAISE, which were sustained to Week 60 in RAISE-XT.
In the Phase 3 RAISE study, zilucoplan significantly improved fatigue in MG patients, with sustained benefits through Week 60 in the RAISE-XT extension.
Recommendations for the management of myasthenia gravis in Belgium
Source : https://pubmed.ncbi.nlm.nih.gov/38649556/
International guidelines on the treatment of myasthenia gravis (MG) have been published but are not tailored to the Belgian situation. This publication presents recommendations from a group of Belgian MG...
Belgian MG experts present tailored recommendations for managing generalized and ocular myasthenia gravis, addressing treatment sequences, comorbidities, and future therapies. A guide for Belgian neurologists.
Effects of acupuncture treatment for myasthenia gravis: A systematic review and meta-analysis
Source : https://pubmed.ncbi.nlm.nih.gov/38165870/
This meta-analysis demonstrated that acupuncture as an auxiliary may play a positive role in treating MG. It can improve the effective rate of treatment, and reduce TCM relative clinical score,...
Acupuncture may improve treatment efficacy and reduce clinical scores in myasthenia gravis. However, due to low study quality, further high-quality RCTs are needed to confirm these findings.
MuSK Myasthenia Gravis-Potential Pathomechanisms and Treatment Directed against Specific Targets
Source : https://pubmed.ncbi.nlm.nih.gov/38534400/
Myasthenia gravis (MG) is an autoimmune disease in which autoantibodies target structures within the neuromuscular junction, affecting neuromuscular transmission. Muscle-specific tyrosine kinase receptor-associated MG (MuSK-MG) is a rare, often more...
MuSK-MG, a severe subtype of myasthenia gravis, involves distinct pathomechanisms and requires specialized treatments; ongoing research aims to improve understanding and therapy options.
The Role of Thymoma and Thymic Hyperplasia as Prognostic Risk Factors for Secondary Generalisation in Adults with Ocular Myasthenia Gravis: A Systematic Narrative Review
Source : https://pubmed.ncbi.nlm.nih.gov/38046270/
This review provides evidence for the consideration of thymectomy early after thymomatous OMG diagnosis to prevent GMG conversion. As the review did not collect enough evidence to support the influence...
This review provides evidence for the consideration of thymectomy early after thymomatous OMG diagnosis to prevent GMG conversion. As the review did not collect enough evidence to support the influence of thymic hyperplasia on OMG conversion, further research is required.