Thymoma-associated autoimmune encephalitis with myasthenia gravis: Case series and literature review
Source : https://pubmed.ncbi.nlm.nih.gov/38421083/
There was no significant difference in the clinical manifestations between these patients and others with only TAMG or TAAE. TAAE was commonly associated with AMPAR2-Ab. Significantly, AE more commonly heralded...
Thymoma-associated autoimmune encephalitis (TAAE) commonly signals thymoma recurrence and is associated with AMPAR2 antibodies. Autoimmune encephalitis onset is a more frequent indicator of recurrence than myasthenia gravis onset.
Efgartigimod-associated Kaposi's varicelliform eruption and herpetic conjunctivitis in a patient with seropositive ocular myasthenia gravis: a case report and review
Source : https://pubmed.ncbi.nlm.nih.gov/39148733/
This case is the first report of a patient with KVE and herpetic conjunctivitis related to efgartigimod in PubMed. This is rare and unusual. Clinicians should be alert to the...
A 60-year-old man with ocular myasthenia gravis developed Kaposi's varicelliform eruption and herpetic conjunctivitis after efgartigimod treatment, highlighting rare complications requiring clinician awareness.
Does Surgical Removal of the Thymus Have Deleterious Consequences
Source : https://pubmed.ncbi.nlm.nih.gov/38781559/
The role of immunosenescence, particularly the natural process of thymic involution during aging, is increasingly acknowledged as a factor contributing to the development of autoimmune diseases and cancer. Recently, a...
Thymectomy benefits patients with MG and thymoma, outweighing risks of cancer and autoimmunity, but incidental thymus removal during other surgeries should be minimized to avoid potential long-term consequences.
Myasthenia gravis: the future is here
Source : https://pubmed.ncbi.nlm.nih.gov/39105625/
Myasthenia gravis (MG) stands as a prototypical antibody-mediated autoimmune disease: it is dependent on T cells and characterized by the presence of autoantibodies targeting proteins located on the postsynaptic surface...
Advancements in understanding MG subgroups have led to targeted therapies, improving treatment precision and outcomes in this autoimmune neuromuscular disorder.
Refocusing generalized myasthenia gravis: Patient burden, disease profiles, and the role of evolving therapy
Source : https://pubmed.ncbi.nlm.nih.gov/38117543/
gMG has a physical, mental, and social impact, resulting in a considerable burden of disease and substantially decreased QoL, despite standard treatments. The availability of novel, targeted treatments that influence...
Novel targeted treatments and biomarkers offer the potential to optimize management of generalized myasthenia gravis, improving patient outcomes, and reducing disease burden and enhancing quality of life.