The gut brain axis is so crucial.

Important to do thorough evaluation in patient as Migraine has been associated with gastrointestinal (GI) dysfunction. For instance, GI complaints increase with increasing headache frequency, migraines are often accompanied by various GI symptoms, and patients with migraine are more prone to GI disorders

Key Points
• Conclusion/Relevance: “In this review, we emphasized the substantial overlap between feeding behavior, energy metabolism and migraine. The fact that specific neuronal populations govern appetite and play a role in migraine pathophysiology is relevant because unlocking this overlap of neural networks will help determine locations (and its pharmacology) with which to target for migraine therapy.”
• Migraine therapeutic targets exert strong input on appetite neuronal circuits. Furthermore, various neuropeptidergic systems could be good drug targets for migraine treatment.
• The authors noted that due to a lack of randomized-controlled trials, specific dietary restrictions and other lifestyle modifications do not constitute evidence-based recommendations to treat or prevent migraines. Furthermore, skipping meals may not be a migraine trigger but instead an early premonitory manifestation. This statement is in line with the hypothesis that some perceived migraine triggers may be premonitory symptoms..