Have you treated patients with two cGRP inhibitors together as a preventive?
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50 yo woman with long history of migraine doing somewhat better on Botox but still overusing abortives, which cGRP inhibitor would you suggest adding on?
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Acute Treatment of Migraine in Adolescents: Real-World Analysis of Remote Electrical Neuromodulation (REN)
Source : https://www.pedneur.com/article/S0887-8994(23)00055-3/fulltext
Nearly 10% of children and adolescents in the United States experience migraine. Pharmacological treatment of migraine in adolescents is limited due to only few FDA approved medications, limited efficacy, or...
Conclusions/Relevance: This real-world analysis demonstrates the persistent efficacy of REN for abortive treatment of migraine in adolescents, extending findings of prior clinical trials in adolescents and real-world studies in adults.
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Huma Sheikh, CEO, NY Neurology Medicine, PCMay 05, 2023This is great to have alternatives.
Comparison of Migraine Characteristics in Patients With and Without Inflammatory Bowel Disease: A Retrospective Cohort Study - PubMed
Source : https://pubmed.ncbi.nlm.nih.gov/36960555/
Migraine with and without aura have increased prevalence in IBD patients. Further study of this topic will be helpful to clarify the prevalence of migraine, establish this population's response to...
Conclusions: Migraine with and without aura have increased prevalence in IBD patients. Further study of this topic will be helpful to clarify the prevalence of migraine, establish this population’s response to treatment, and better understand the reason(s) for a low rate of treatment.
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Huma Sheikh, CEO, NY Neurology Medicine, PCMay 05, 2023This is a good read.
The patent foramen ovale may alter migraine brain activity: A pilot study of electroencephalography spectrum and functional connectivity analysis
Source : https://www.frontiersin.org/articles/10.3389/fnmol.2023.1133303/full
BackgroundA link has been shown between patent foramen ovale (PFO) and migraine, particularly migraine with aura. However, it is unknown if PFO might cause migraine by altering cortical excitability and...
Conclusion: The outcomes of this investigation suggested that PFO may change the cortical excitability in the occipital lobe of both migraineurs with and without aura. Meanwhile, the beta band PSD on the occipital area during photic stimulation might be an objective measure of severity in migraineurs with PFO.
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Huma Sheikh, CEO, NY Neurology Medicine, PCMay 05, 2023This may be how it can contribute to migraine.