Migraine Connect
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Grey and white matter alteration in patients with patent foramen ovale: A cross-sectional observational study using combined surface-based morphometry and voxel-based morphometry. - PubMed

Grey and white matter alteration in patients with patent foramen ovale: A cross-sectional observational study using combined surface-based morphometry and voxel-based morphometry. - PubMed

Source : https://pubmed.ncbi.nlm.nih.gov/42601697

Study reveals brain changes in migraine patients with patent foramen ovale, noting some findings lacked statistical significance, highlighting potential neural substrates related to migraine symptoms.


Migraineurs with patent foramen ovale exhibit gray and white matter volume reductions in pain, cognition, and emotion-related brain regions, though some findings lacked statistical significance post-correction.

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A Systematic Literature Review of Emerging Advances in Neurological Disorders: Diagnostic Innovations, Therapeutic Strategies, and Future Directions. - PubMed

A Systematic Literature Review of Emerging Advances in Neurological Disorders: Diagnostic Innovations, Therapeutic Strategies, and Future Directions. - PubMed

Source : https://pubmed.ncbi.nlm.nih.gov/42565151

Explore innovations in neurology, including radiomics and biologics, with potential in stroke and Alzheimer's. Larger trials and validation needed for clinical use.


Recent advances in radiomics, circulating tumor DNA, and biologics show potential in conditions like stroke, Alzheimer's, and Parkinson's but need larger trials and validation.

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Pituitary Apoplexy Without Chiasmal Compression Presenting With Radiographic Oculomotor Nerve Compression in a Prolactinoma: A Case Report. - PubMed

Pituitary Apoplexy Without Chiasmal Compression Presenting With Radiographic Oculomotor Nerve Compression in a Prolactinoma: A Case Report. - PubMed

Source : https://pubmed.ncbi.nlm.nih.gov/42535139

A case of pituitary apoplexy in prolactinoma shows oculomotor nerve compression without optic chiasm involvement, highlighting the need for awareness of atyp...


Pituitary apoplexy can present with oculomotor nerve compression without optic chiasm involvement. Clinicians should consider this in prolactinoma cases with atypical cranial neuropathy. Disease Condition: Pituitary Apoplexy. Specialty Focus: Neurology.

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Interictal burden in migraine: a systematic review of conceptual domains and measurement properties of instruments. - PubMed

Interictal burden in migraine: a systematic review of conceptual domains and measurement properties of instruments. - PubMed

Source : https://pubmed.ncbi.nlm.nih.gov/42498937

Discover how MIBS-4 measures interictal burden in migraine, highlighting its construct validity and responsiveness.


MIBS-4 is used to assess migraine interictal burden, with evidence concentrated in construct validity and responsiveness. Further psychometric studies are needed.

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A delayed endothelial-glial mechanism for CGRP-induced migraine. - PubMed

A delayed endothelial-glial mechanism for CGRP-induced migraine. - PubMed

Source : https://pubmed.ncbi.nlm.nih.gov/42464096

Explore how CGRP-induced signaling, involving transcription and ion channel changes, might contribute to delayed migraine pain, offering insights into potential new treatments.


CGRP may trigger delayed migraine pain via endothelial-glial signaling, involving transcription processes and ion channel modulation, suggesting new therapeutic targets.