miR-155 and functional proteins of CD8+ T cells as potential prognostic biomarkers for relapsing-remitting multiple sclerosis

Source : https://msard-journal.com/retrieve/pii/S221103482100345X

Multiple sclerosis (MS) is a chronic autoimmune disease of the central nervous system (CNS) usually caused by a combination of genetic and environmental factors. It is characterized by recurrent episodes...

An algorithm using clinical data to predict the optimal individual glucocorticoid dosage to treat multiple sclerosis relapses - Judit Gili-Kovács, Robert Hoepner, Anke Salmen, Maud Bagnoud, Ralf Gold, Andrew Chan, Myriam Briner, 2021

Source : https://journals.sagepub.com/doi/10.1177/17562864211020074

Abstract Background: Glucocorticoid (GC) pulse therapy is used for multiple sclerosis (MS) relapse treatment; however, GC resistance is a common problem. Considering that GC dosing is individual with several response-influencing...

Microstructural MRI Correlates of Cognitive Impairment in Multiple Sclerosis: The Role of Deep Gray Matter

Source : https://www.mdpi.com/2075-4418/11/6/1103

Although cognitive impairment (CI) is frequently observed in people with multiple sclerosis (pwMS), its pathogenesis is still controversial. Conflicting results emerged concerning the role of microstructural gray matter (GM) damage...