Advancements in multiple sclerosis - PubMed
Source : https://pubmed.ncbi.nlm.nih.gov/40171883/
The global prevalence of multiple sclerosis (MS) is increasing, and early diagnosis and treatment is essential in mitigating disability. While recent therapeutic advancements have significantly reduced relapse rates, the progressive...
Review highlights advances in multiple sclerosis including updated McDonald criteria, early treatment strategies, emerging biomarkers, and novel therapies such as CAR-T cells and EBV-targeted vaccines to improve disease outcomes.
The role of cannabinoid ligands in neurodegenerative diseases: emerging anti-inflammatory, immunomodulation and disease-modifying perspectives - PubMed
Source : https://pubmed.ncbi.nlm.nih.gov/41937092/
Neurodegenerative diseases (NDs) constitute a growing global health burden driven by population aging and remain without disease-modifying therapies. Although chronic neuroinflammation and aberrant protein aggregation are widely recognized as shared...
Endocannabinoid system modulation shows anti-inflammatory and neuroprotective potential across neurodegenerative diseases, including multiple sclerosis, though clinical translation remains limited by receptor specificity, safety concerns, and incomplete understanding of long-term effects.
Advancing consensus priorities for high-impact provider behaviors in multiple sclerosis care: A Delphi study - PubMed
Source : https://pubmed.ncbi.nlm.nih.gov/41905021/
This study identified a consensus-driven set of measurable provider behaviors relevant to high-quality MS care, forming a practical framework for evaluating the effectiveness of Project ECHO MS. Future research may...
Delphi study identifies consensus provider behaviors in multiple sclerosis care, including timely diagnosis, DMT optimization, patient-centered communication, and multidisciplinary coordination, offering a framework to improve care quality and outcomes.
Patterns of emergency department utilization among persons with multiple sclerosis across seven medical institutions - PubMed
Source : https://pubmed.ncbi.nlm.nih.gov/41865560/
These findings can guide efforts to address systemic inequities, and individual healthcare needs to improve MS management.
Observational study shows higher emergency department utilization in multiple sclerosis among marginalized populations, driven by social determinants, lack of neurology care, and insurance disparities, highlighting inequities impacting disease management outcomes.
Study evaluating advance care planning conversations in progressive multiple sclerosis found neurologists demonstrated strong communication skills and emotional responsiveness, though shared decision-making performance remained moderate despite specialized ACP training.