Real-world experience of ocrelizumab in multiple sclerosis in an arab population
Source : https://doi.org/10.1080/21556660.2021.1989193
Multiple sclerosis (MS) is a chronic autoimmune disease that targets the central nervous system and leads to progressive neuro-axonal demyelination eventually resulting in neurological disability and cognitive impairment. MS presents...
Signs of neuroinflammation outweigh neurodegeneration as predictors for early conversion to MS - The Egyptian Journal of Neurology, Psychiatry and Neurosurgery
Source : https://link.springer.com/article/10.1186/s41983-021-00356-7
Background The pathophysiological mechanisms underlying multiple sclerosis include both inflammatory and degenerative processes. We aimed to study and compare markers of neuroinflammation and neurodegeneration in patients with first presentation of...
Methylprednisolone stimulated gene expression (GILZ, MCL-1) and basal cortisol levels in multiple sclerosis patients in relapse are associated with clinical response - Scientific Reports
Source : https://www.nature.com/articles/s41598-021-98868-y
Glucocorticoids (GCs) are the main treatment of relapse in multiple sclerosis (MS). Decreased sensitivity to GCs in MS patients has been associated with lack of the suppressive effect of GCs...