Elevated sCD40L in Secondary Progressive Multiple Sclerosis in Comparison to Non-progressive Benign and Relapsing Remitting Multiple Sclerosis - PubMed
Source : https://pubmed.ncbi.nlm.nih.gov/34720605/
1 Department of Neurology, University of Michigan Medical School, Ann Arbor, MI, USA. 2 Autoimmunity Center of Excellence, University of Michigan Medical School, Ann Arbor, MI, USA. 3 Graduate Program...
Conclusions: These differences may facilitate personalized precision medicine and aid in the discovery of new therapeutic targets for disease progression through the improvement of patient stratification.
Conclusions: Performance in information processing speed might help to identify patients at risk for physical impairment. Therefore, neuropsychological assessment should be integrated in clinical standard care to support disease management in pwMS.
Nucleic Acids as Novel Therapeutic Modalities to Address Multiple Sclerosis Onset and Progression - Cellular and Molecular Neurobiology
Source : https://link.springer.com/article/10.1007/s10571-021-01158-4
The issue of treating Multiple Sclerosis (MS) begins with disease-modifying treatments (DMTs) which may cause lymphopenia, dyspnea, and many other adverse effects. Consequently, further identification and evaluation of alternative treatments...
Rim lesions are demonstrated in early relapsing-remitting multiple sclerosis using 3 T-based susceptibility-weighted imaging in a multi-institutional setting - Neuroradiology
Source : https://link.springer.com/article/10.1007/s00234-021-02768-x
Purpose Rim lesions, characterised by a paramagnetic rim on susceptibility-based MRI, have been suggested to reflect chronic inflammatory demyelination in multiple sclerosis (MS) patients. Here, we assess, through susceptibility-weighted imaging...