Mindfulness training during brief periods of hospitalization in multiple sclerosis (MS): beneficial alterations in fatigue and the mediating role of depression - BMC Neurology
Source : https://bmcneurol.biomedcentral.com/articles/10.1186/s12883-021-02390-7
Objectives Persons with MS (PwMS) are frequently affected by fatigue and depression. Mindfulness-based interventions may reduce these symptoms in PwMS and consequently their application has been extended to various settings....
Conclusion: Results of the current study indicate that short-term mindfulness training during brief periods of hospitalization may be beneficial for PwMS. They further complement previous work by identifying depression as a potential mediator of the antagonistic relationship between mindfulness and fatigue. Based on the current exploratory...
Ocrelizumab treatment in multiple sclerosis: A Danish population-based cohort study - PubMed
Source : https://pubmed.ncbi.nlm.nih.gov/34644452/
doi: 10.1111/ene.15142. Online ahead of print. 1 The Danish Multiple Sclerosis Registry, Copenhagen University Hospital-Rigshospitalet, Copenhagen, Denmark. 2 Danish Multiple Sclerosis Center, Copenhagen University Hospital-Rigshospitalet, Copenhagen, Denmark. 3 Odense University...
Conclusions: It is shown that most MS patients treated with ocrelizumab are clinically stabilized and with an adverse event profile consistent with the experience from the pivotal clinical trials.
Conclusions: Our case series showed that TLE and MS symptoms may resemble the symptoms of ALE. Diagnosing of overlapping MS and ALE could not be made definitively because neither clinical symptoms nor temporomesial MRI findings could help clearly to distinguish between MS and antibody-negative ALE.
This disease-specific hiPSC line will be useful for studying PPMS in vitro, allowing the generation of immune and CNS cell types.
Role of lipoic acid in multiple sclerosis
Source : https://onlinelibrary.wiley.com/doi/full/10.1111/cns.13793
Hongsheng Xie , Xiufang Yang , Yuan Cao , Xipeng Long , Huifang Shang , Zhiyun Jia , Corresponding Author Zhiyun Jia Department of Nuclear Medicine, West China Hospital, Sichuan...
In conclusion, this review provides evidence for the anti-inflammatory and antioxidative effects of LA in both in vitro and in vivo experiments; therefore, patients with MS may benefit from LA administration. Whether LA can be a routine supplementary therapy warrants further study.