Multiple sclerosis and amyotrophic lateral sclerosis: is there an association or a red flag? A case report and literature review - PubMed
Source : https://pubmed.ncbi.nlm.nih.gov/39217293/
The co-occurrence of ALS and MS is extremely rare, but it can be explained by pathogenesis related to neurodegeneration, inflammation, or genetic susceptibility. Rapid progressive motor and bulbar symptoms could...
A 46-year-old female with MS-like symptoms developed rapid progression, bulbar dysfunction, and muscle atrophy. Neurophysiological tests confirmed ALS. Co-occurrence of ALS and MS, though rare, may involve neurodegeneration and inflammation.
Risk of multiple sclerosis in patients with psoriasis receiving anti-IL-17 agents: A case-based review - PubMed
Source : https://pubmed.ncbi.nlm.nih.gov/38345289/
Biologics approved for psoriasis exhibit favorable safety profiles, and serious adverse events have rarely been reported. In this report, we present the case of a patient treated with ixekizumab, an...
This case report discusses a patient developing multiple sclerosis after ixekizumab treatment for psoriasis. While rare, possible inflammatory events in the central nervous system with anti-IL-17 agents warrant consideration.
Modulating the Gut Microbiome in Multiple Sclerosis Management: A Systematic Review of Current Interventions - PubMed
Source : https://pubmed.ncbi.nlm.nih.gov/38137679/
This review attempted to explore all recent clinical studies that have investigated the clinical and autoimmune impact of gut microbiota interventions in multiple sclerosis (MS), including dietary protocols, probiotics, fecal...
Recent studies highlight the positive impact of gut microbiota interventions (diet, probiotics, FMT, IF) on multiple sclerosis, improving relapse rates, disability scores, fatigue, inflammation, mood, and quality of life.
Tumor or Demyelination? Three Tumefactive Multiple Sclerosis Case Reports and Literature Review - PubMed
Source : https://pubmed.ncbi.nlm.nih.gov/38641243/
TMS is difficult to differentiate from brain tumors. It is necessary to improve the understanding of these diseases, to apply the correct diagnosis and treatment and to avoid unnecessary invasive...
Tumefactive multiple sclerosis (TMS) can mimic brain tumors with large lesions. Early diagnosis, understanding, and proper treatment are crucial to avoid unnecessary surgery and ensure accurate management.
Immunomodulators and immunosuppressants for progressive multiple sclerosis: a network meta-analysis - PubMed
Source : https://pubmed.ncbi.nlm.nih.gov/39254048/
The number of people with PMS with relapses is probably slightly reduced with rituximab at two years, and interferon beta-1b at three years, compared to placebo. Both drugs are also...
This network meta-analysis evaluated 23 studies on treatments for progressive multiple sclerosis, finding limited evidence on efficacy and safety, with rituximab and interferon beta-1b showing slight relapse reduction compared to placebo.