Fluid biomarkers in multiple sclerosis: from current to future applications - PubMed
Source : https://pubmed.ncbi.nlm.nih.gov/39444698/
Multiple sclerosis (MS) is an immune-mediated inflammatory and degenerative disorder of the central nervous system (CNS) with heterogeneous clinical manifestations. In the last decade, the landscape of cerebrospinal fluid (CSF)...
This article explores cerebrospinal fluid (CSF) and blood biomarkers for multiple sclerosis (MS), highlighting their role in diagnosis, prognosis, treatment monitoring, and personalized management, while addressing real-world challenges.
Factors Contributing to the Development of Neuropsychiatric Manifestations in Persons With Multiple Sclerosis: A Systematic Review - PubMed
Source : https://pubmed.ncbi.nlm.nih.gov/39246867/
Multiple sclerosis (MS) is the most common chronic demyelinating disease affecting the central nervous system (CNS) and is distinguished by neuroinflammation and neurodegeneration. It has four categories based on clinical...
This systematic review explores factors influencing neuropsychiatric manifestations in multiple sclerosis, including brain changes, immune mechanisms, socioeconomic, and individual factors, highlighting the need for further research to improve patient outcomes.
A case report and review of rheumatoid arthritis co-occurring with tuberous sclerosis complex, a rare occurrence - PubMed
Source : https://pubmed.ncbi.nlm.nih.gov/39391300/
Rheumatoid arthritis (RA) is a common autoimmune disease. Tuberous sclerosis complex(TSC) is a rare autosomal dominant disorder. We report a case of RA with TSC. The patient was a 46-year-old...
A 46-year-old woman with RA and persistent cough was diagnosed with TSC after further evaluation revealed lymphangioleiomyomatosis, angiomyolipomas, subependymal nodules, and other TSC features. Everolimus improved her symptoms.
Solitary atrial Rhabdomyoma in an infant with tuberous sclerosis: a case report and review of the literature - PubMed
Source : https://pubmed.ncbi.nlm.nih.gov/38062408/
Despite CR's predominance in the ventricles, a diagnosis of rhabdomyoma should be kept in mind in the presence of a solitary atrial mass and PACs. Physicians should evaluate systemic findings...
A 7-day-old neonate with atrial fibrillation, PACs, and a right atrial rhabdomyoma was diagnosed with tuberous sclerosis complex (TSC) based on systemic findings, managed with anti-convulsants, and monitored without surgery.
The diagnosis of multiple sclerosis: what has changed in diagnostic criteria? - PubMed
Source : https://pubmed.ncbi.nlm.nih.gov/38362016/
Multiple sclerosis (MS) is a chronic, demyelinating disease affecting the central nervous system. Diagnosis of MS is based on the proof of disease dissemination in time (DIT) and dissemination in...
The review highlights key updates in the 2017 McDonald criteria for diagnosing multiple sclerosis, emphasizing the inclusion of oligoclonal bands, symptomatic lesions, and their impact on early, accurate diagnosis and treatment.