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Day 2 & 3 Highlights from the 2022 American Academy of Neurology Fall Conference

The American Academy of Neurology (AAN) 2022 Fall Conference featured the latest on diagnosing and treating dementia, epilepsy, movement disorders, headache, and other brain disorders, with content developed by neurologists for neurologists. The three-day hybrid AAN Fall Conference included in-person-only preconference programming for advanced practice providers plus a sports concussion workshop for general neurologists and subspecialists as well as anyone who treats sports injuries – specifically concussions – in their practice.

Click above for a summary of conference highlights.

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Day 2 & 3 Highlights from the 2022 American Academy of Neurology Fall Conference - Cloned

The American Academy of Neurology (AAN) 2022 Fall Conference featured the latest on diagnosing and treating dementia, epilepsy, movement disorders, headache, and other brain disorders, with content developed by neurologists for neurologists. The three-day hybrid AAN Fall Conference included in-person-only preconference programming for advanced practice providers plus a sports concussion workshop for general neurologists and subspecialists as well as anyone who treats sports injuries – specifically concussions – in their practice.

Click above for a summary of conference highlights.

 

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Reemergence of pathogenic, autoantibody-producing B cell clones in myasthenia gravis following B cell depletion therapy - Acta Neuropathologica Communications

Reemergence of pathogenic, autoantibody-producing B cell clones in myasthenia gravis following B cell depletion therapy - Acta Neuropathologica Communications

Source : https://actaneurocomms.biomedcentral.com/articles/10.1186/s40478-022-01454-0

Myasthenia gravis (MG) is an autoantibody-mediated autoimmune disorder of the neuromuscular junction. A small subset of patients (<10%) with MG, have autoantibodies targeting muscle-specific tyrosine kinase (MuSK). MuSK MG patients...


Conclusions: This study provides both a mechanistic understanding of MuSK MG relapse and a valuable candidate biomarker for relapse prediction.

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Risk factors associated with adverse pregnancy outcomes and postpartum exacerbation in women with myasthenia gravis - PubMed

Risk factors associated with adverse pregnancy outcomes and postpartum exacerbation in women with myasthenia gravis - PubMed

Source : https://pubmed.ncbi.nlm.nih.gov/36305609/

Most MG patients have unaffected courses during pregnancy but face a higher rate of maternal and fetal complications. Risk factors identified in our study aid the management of pregnancy in...


Conclusions: "Conclusions: Most MG patients have unaffected courses during pregnancy but face a higher rate of maternal and fetal complications. Risk factors identified in our study aid the management of pregnancy in MG women."


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Like a Game of Chess, Every Move Matters: The Role of Antibodies in the Myasthenia Gravis Treatment Landscape

Like a Game of Chess, Every Move Matters: The Role of Antibodies in the Myasthenia Gravis Treatment Landscape

Source : https://www.psychiatrist.com/pcc/neurologic/role-of-antibodies-in-myasthenia-gravis-treatment/

ABSTRACT Symptoms and disease pathophysiology of myasthenia gravis (MG) vary considerably with each patient, and their individual preferences and priorities add to the need for individualized treatment of this autoimmune...


Conclusions: Research in MG has grown substantially in recent years. New treatments have the potential of being both effective and well tolerated, addressing the trade-off of choosing either efficacy or tolerability when selecting treatments. Promising investigational treatments that may become available in the future may allow more patients...