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Thymus Surgery Prospectives and Perspectives in Myasthenia Gravis - PubMed

Thymus Surgery Prospectives and Perspectives in Myasthenia Gravis - PubMed

Source : https://pubmed.ncbi.nlm.nih.gov/38540983/

The thymus is a lymphoid organ involved in the differentiation of T cells, and has a central role in the physiopathogenesis of Myasthenia Gravis (MG). This connection is proved by...

The paper reviews thymectomy's role in Myasthenia Gravis treatment, highlighting its impact on T cell differentiation, neuromuscular junctions, and hospital stay reductions through minimally invasive surgical techniques.

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Myasthenia Gravis with Toxic Goiter: Challenges with Management in a Low-Resource Setting in Africa; Review of Literature and Case Report - PubMed

Myasthenia Gravis with Toxic Goiter: Challenges with Management in a Low-Resource Setting in Africa; Review of Literature and Case Report - PubMed

Source : https://pubmed.ncbi.nlm.nih.gov/38317049/

Myasthenia gravis (MG) is an antibody-mediated autoimmune disease with the cardinal feature being exertional voluntary skeletal muscle weakness and fatigability. It can be an isolated finding or in association with...

A 24-year-old with myasthenia gravis and toxic goiter underwent thymectomy and subtotal thyroidectomy, achieving satisfactory outcomes. This case highlights the coexistence of MG with thymoma and goiter.

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1yr
American Association of Neuromuscular & Electrodiagnostic Medicine Annual Meeting

Taking place at the Savannah Convention Center and Westin Savannah Harbor in Georgia, the 2024 annual meeting of the American Association of Neuromuscular & Electrodiagnostic Medicine (AANEM) spans four days and features the latest advances in neuromuscular and musculoskeletal disorders and electrodiagnostic medicine, including emerging gene therapies and new technologies. The meeting also includes sessions by the Myasthenia Gravis Foundation of America, Peripheral Nerve Society, and Dysautonomia International.

Above, we summarize some presentations that caught our eye at the conference. We will follow this up with a postconference wrap-up report. Stay tuned.

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An angel or a devil? Current view on the role of CD8+ T cells in the pathogenesis of myasthenia gravis

An angel or a devil? Current view on the role of CD8+ T cells in the pathogenesis of myasthenia gravis

Source : https://pubmed.ncbi.nlm.nih.gov/38378668/

Further studies on CD8 + T cells in MG are necessary to determine, among others, the real pattern of the Vβ gene usage of autoantigen-specific CD8 + cells in patients...

Further studies on CD8+ T cells in MG are needed to explore autoantigen-specific subsets, including Tc1, Tc17, and IL-17+IFN-γ+CD8+ T cells, and CD20+ and CXCR5+ CD8 T cells.

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1yr
Advances in Understanding and Managing Myasthenia Gravis: Current Trends and Future Directions

Advances in Understanding and Managing Myasthenia Gravis: Current Trends and Future Directions

Source : https://pubmed.ncbi.nlm.nih.gov/38803727/

Myasthenia gravis (MG) is an autoimmune illness characterized by autoantibodies against the acetylcholine receptor (AChR), muscle-specific tyrosine kinase (MuSK), and an increasing number of extra postsynaptic proteins. Pathogenic autoantibodies reduce...

Myasthenia gravis is an autoimmune disorder causing muscle weakness, primarily due to autoantibodies targeting AChR. Treatment focuses on managing symptoms via immune modulation, including complement inhibition and plasmapheresis.