The 2025 annual meeting of the American Association of Neuromuscular & Electrodiagnostic Medicine (AANEM) spans four days and is taking place in San Francisco, along with an option to participate virtually. The meeting brings physicians, technologists, advanced practice providers, and other health care professionals together to learn about the latest advances in neuromuscular medicine, electrodiagnostic medicine, neuromuscular ultrasound, and more, with presentations and posters covering the influx of new therapies and technologies.

Click above to access a full summary of sessions so far.

Functional neurological disorder (FND) is a disabling neuropsychiatric condition characterized by involuntary motor, sensory, or cognitive symptoms that are not explained by identifiable structural pathology. Once considered purely psychogenic, FND is now increasingly understood as a condition involving abnormal brain network connectivity and shaped by biopsychosocial factors.

Highlights:

• FND is the second most common diagnosis in outpatient neurology, disproportionately affecting women and often emerging in early adulthood.
• Neuroimaging studies reveal altered connectivity in circuits governing emotion, motor control, and self-agency, supporting FND as a genuine brain-based disorder.
• Symptoms may include functional tremors, gait impairment, non-dermatomal sensory changes, and cognitive difficulties that do not align with classical neurological patterns.
• Diagnosis increasingly focuses on “positive signs” of internal inconsistency and incongruence during neurologic examination, rather than exclusion of other diseases.
• Optimal management requires a multidisciplinary approach—including neurology, psychiatry, psychology, and rehabilitation medicine.
• Emerging predictive imaging techniques may enable future personalization of treatment strategies.

What sets this study apart:

This review underscores the evolution in how FND is diagnosed and treated—shifting from misdiagnosis and stigma toward evidence-based, multidisciplinary care. It highlights the need for early recognition, tailored interventions, and the continued development of objective diagnostic tools.

Limitations:

Challenges remain, including diagnostic uncertainty, persistent stigma, and the absence of standardized imaging protocols or individualized treatment pathways based on neurobiological profiles.

What role could predictive imaging play in guiding individualized treatment plans for FND?

The Immunoglobulin National Society (IgNS) National Conference is considered the premier annual event for clinicians, business professionals, and industry in the Ig therapy and biologics space. Attendees have access to preclinical and clinical studies, peer-to-peer collaboration, and professional development.

Above please find our postconference wrap-up report with summaries of research and presentations that caught our eye at the meeting.