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Did you know? The American Psychiatric Association recommends structured psychotherapy—like Dialectical Behavior Therapy and Mentalization-Based Treatment—as the gold standard for Borderline Personality Disorder, with medication used only for specific symptoms and always alongside therapy. Person-centered plans and collaboration are key.

Did you know that clinicians are encouraged to use standardized symptom scales at the start of BPD treatment to track progress over time?

NCCN Guidelines

Did you know that clinicians are encouraged to use standardized symptom scales at the start of BPD treatment to track progress over time?

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5mo
Subtype-specific atypical B cell profiles in myasthenia gravis reveal distinct immunopathological pathways - PubMed

Subtype-specific atypical B cell profiles in myasthenia gravis reveal distinct immunopathological pathways - PubMed

Source : https://pubmed.ncbi.nlm.nih.gov/40607384/

MG subtypes exhibit distinct atBC profiles linked to immunopathology and disease onset. These findings reveal subtype-specific pathways that regulate atBCs and highlight their potential as therapeutic targets in both IgG1-3-...

Distinct atypical B cell profiles in AChR+ and MuSK+ myasthenia gravis subtypes suggest unique immune pathways and treatment responses, supporting future B cell–targeted, subtype-specific therapeutic strategies in gMG.

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5mo
Emergent role of complement inhibitors in myasthenic crisis: Understanding why, when and how - PubMed

Emergent role of complement inhibitors in myasthenic crisis: Understanding why, when and how - PubMed

Source : https://pubmed.ncbi.nlm.nih.gov/40505554/

We report the case of a 32-year-old woman with an 11-year history of thymomatous AChR antibody-positive generalized myasthenia gravis (gMG, MGFA IIIb) who experienced a myasthenic crisis (MC) during the...

A postpartum woman with AChR+ gMG and myasthenic crisis improved rapidly after eculizumab treatment. Literature review supports complement inhibition as an option for patients unresponsive to standard crisis therapies.

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5mo
Network connectivity, between-study heterogeneity and timepoint challenges in generalized myasthenia gravis: a feasibility assessment of indirect treatment comparisons - PubMed

Network connectivity, between-study heterogeneity and timepoint challenges in generalized myasthenia gravis: a feasibility assessment of indirect treatment comparisons - PubMed

Source : https://pubmed.ncbi.nlm.nih.gov/40321129/

Aim: We performed a feasibility assessment to systematically evaluate randomized controlled trials (RCTs) for generalized myasthenia gravis (gMG) treatments. The goal was to identify the advantages and disadvantages of different...

This study assesses the feasibility of indirect treatment comparisons in gMG, identifying challenges like trial heterogeneity, dosing inconsistencies, and treatment effect modifiers, suggesting multi-method ITC approaches to minimize bias.