A Framework for Estimating the Eligible Patient Population for New Migraine Acute Therapies in the United States

Source : https://link.springer.com/article/10.1007/s12325-021-01781-z

Introduction Migraine is associated with considerable disability for patients not adequately managed with current standards of care. New acute therapies may offer relief for this population of patients; however, population...

Safety and tolerability evaluation of erenumab for the preventive treatment of migraine

Source : https://www.tandfonline.com/doi/abs/10.1080/14740338.2021.1933941

Abstract Introduction: Erenumab, a monoclonal antibody targeting the receptor of calcitonin gene related peptide (CGRP), is the first disease-specific and mechanism-based treatment approved for the prevention of migraine. Although the...

Early use of erenumab in US real-world practice - Alina Bogdanov, Victoria Chia, Mark Bensink, Robert Urman, Lauren Fischer, Soeren Rasmussen, Christine Szekely, Lee Kallenbach, 2021

Source : https://journals.sagepub.com/doi/full/10.1177/25158163211020419

Background: Erenumab, a monoclonal antibody (mAb) developed to block the calcitonin gene-related peptide (CGRP) receptor, is approved for the prevention of migraine in adults. This retrospective observational study sought to...

Spontaneous coronary artery dissection and migraine crisis: an exceptional combination in male patients | Letters to the Editor

Source : https://doi.org/10.24875/RECICE.M20000158

Home > Letters to the Editor > Spontaneous coronary artery dissection and migraine crisis: an exceptional combination in male patients Available online: 09/21/2020 Disección coronaria espontánea y crisis de migraña:...

Hypervigilance, Allostatic Load, and Migraine Prevention: Antibodies to CGRP or Receptor

Source : https://link.springer.com/article/10.1007/s40120-021-00250-7

Migraine involves brain hypersensitivity with episodic dysfunction triggered by behavioral or physiological stressors. During an acute migraine attack the trigeminal nerve is activated (peripheral sensitization). This leads to central sensitization...