Repeated oxytocin prevents central sensitization by regulating synaptic plasticity via oxytocin receptor in a chronic migraine mouse model - The Journal of Headache and Pain
Source : https://thejournalofheadacheandpain.biomedcentral.com/articles/10.1186/s10194-021-01299-3
Background Central sensitization is one of the characters of chronic migraine (CM). Aberrant synaptic plasticity can induce central sensitization. Oxytocin (OT), which is a hypothalamic hormone, plays an important antinociceptive...
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Huma Sheikh, CEO, NY Neurology Medicine, PC5yrThis is an interesting finding. -
Naveed Saleh, MD, MS – Skipta Team5yrKey Point • Conclusion/Relevance: “Our findings demonstrate that repeated intranasal OT [oxytocin] eliminates central sensitization by regulating synaptic plasticity via OTR [oxytocin receptor] in CM [chronic migraine]. The effect of OT Show More
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Huma Sheikh, CEO, NY Neurology Medicine, PC5yrThere is a lot of overlap.
Erenumab-aooe: A promising monoclonal antibody for prophylactic pharmacotherapy in migraine.
Source : https://rjptonline.org/AbstractView.aspx?PID=2021-14-7-89
Migraine is one form of disorder affecting the quality of life of patient. The term chronic migraine refers to a clinical condition summarized by migraines headache on fifteen days usually...
[Migraine with multiple visual symptoms and out-of-body experience may mimic epilepsy] - PubMed
Source : https://pubmed.ncbi.nlm.nih.gov/34275950/
The patient was an 18-year-old man who had suffered from various visual symptoms as follows since he was 17 years old: 1) a diagonal line appeared in his visual field,...
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Huma Sheikh, CEO, NY Neurology Medicine, PC5yrThe overlap between migraine and epilepsy is very intersting.
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Huma Sheikh, CEO, NY Neurology Medicine, PC5yrThis would make sense since cGRP inhibitors are thought to help with all aspects of migraine.