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Machine prescription for chronic migraine

Source : https://europepmc.org/article/ppr/ppr417374

Responsive to treatment individually, chronic migraine remains strikingly resistant collectively, incurring the second-highest population burden of disability worldwide. A heterogeneity of responsiveness, requiring prolonged-currently heuristic- individual evaluation of available treatments,...


We conclude that the highly distributed mode of causation in chronic migraine necessitates high-dimensional modelling for optimal management. Machine prescription should be considered an essential clinical decision-support tool in the future management of chronic migraine.

  • 4yr
    Key Points • Source: medRxiv • Conclusion/Relevance: “We conclude that the highly distributed mode of causation in chronic migraine necessitates high-dimensional modelling for optimal management. Machine prescription should be considered an essential clinical decision-support Show More
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Huma Sheikh

Preventative migraine treatment is certainly more of an art than science. While algorithms are helpful, they are merely guidelines that practitioners can reference. The cGRP inhibitors have been a game-changer in migraine prevention and I have thought about cGRP inhibitors more and more as first line especially given the now 5 years of safety data for erenumab-aooe. As the cGRP inhibitor market has grown with several that can be used for migraine prevention, I am developing a sense of which to use with whom. For example, I tend to use erenumab-aooe in younger patients with no hx of constipation.

Have you developed a strategy for deciding which cGRP to use with specific types of patients and if one cGRP is not effective, do you switch to another one?

 

  • 4yr
    Thanks for this wonderful contribution [~Huma--Sheikh--huma927@ ]! What insights can others provide regarding the prevention of migraines? In which patients is such intervention particularly effective? Are there some patients who Show More
  • 4yr
    Primarily insurance driven with Nurtec or Ubrelvy.

Show More Comments

  • Saved

Huma Sheikh

Preventative migraine treatment is certainly more of an art than science. While algorithms are helpful, they are merely guidelines that practitioners can reference. The cGRP inhibitors have been a game-changer in migraine prevention and I have thought about cGRP inhibitors more and more as first line especially given the now 5 years of safety data for erenumab-aooe. As the cGRP inhibitor market has grown with several that can be used for migraine prevention, I am developing a sense of which to use with whom. For example, I tend to use erenumab-aooe in younger patients with no hx of constipation.



Have you developed a strategy for deciding which cGRP to use with specific types of patients and if one cGRP is not effective, do you switch to another one?



 


  • 4yr
    Thanks for this wonderful contribution [~Huma--Sheikh--huma927@ ]! What insights can others provide regarding the prevention of migraines? In which patients is such intervention particularly effective? Are there some patients who Show More
  • 4yr
    Primarily insurance driven with Nurtec or Ubrelvy.

Show More Comments

  • Saved

Huma Sheikh

Preventative migraine treatment is certainly more of an art than science. While algorithms are helpful, they are merely guidelines that practitioners can reference. The cGRP inhibitors have been a game-changer in migraine prevention and I have thought about cGRP inhibitors more and more as first line especially given the now 5 years of safety data for erenumab-aooe. As the cGRP inhibitor market has grown with several that can be used for migraine prevention, I am developing a sense of which to use with whom. For example, I tend to use erenumab-aooe in younger patients with no hx of constipation.



Have you developed a strategy for deciding which cGRP to use with specific types of patients and if one cGRP is not effective, do you switch to another one?



 


  • 4yr
    Thanks for this wonderful contribution [~Huma--Sheikh--huma927@ ]! What insights can others provide regarding the prevention of migraines? In which patients is such intervention particularly effective? Are there some patients who Show More
  • 4yr
    Primarily insurance driven with Nurtec or Ubrelvy.

Show More Comments

  • Saved

Huma Sheikh

Preventative migraine treatment is certainly more of an art than science. While algorithms are helpful, they are merely guidelines that practitioners can reference. The cGRP inhibitors have been a game-changer in migraine prevention and I have thought about cGRP inhibitors more and more as first line especially given the now 5 years of safety data for erenumab-aooe. As the cGRP inhibitor market has grown with several that can be used for migraine prevention, I am developing a sense of which to use with whom. For example, I tend to use erenumab-aooe in younger patients with no hx of constipation.



Have you developed a strategy for deciding which cGRP to use with specific types of patients and if one cGRP is not effective, do you switch to another one?



 


  • 4yr
    Thanks for this wonderful contribution [~Huma--Sheikh--huma927@ ]! What insights can others provide regarding the prevention of migraines? In which patients is such intervention particularly effective? Are there some patients who Show More
  • 4yr
    Primarily insurance driven with Nurtec or Ubrelvy.

Show More Comments