Status migrainosus: a potential adverse reaction to Comirnaty (BNT162b2, BioNtech/Pfizer) COVID-19 vaccine-a case report - Neurological Sciences
Source : https://link.springer.com/article/10.1007/s10072-021-05741-x
Background Coronavirus disease-19 (COVID-19) due to acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection is the largest emergency that humanity had to be dealing with in the last century. During the...
Conclusions: In patients with a history of migraine, COVID-19 vaccination could lead to a worsening of headache and, in rare cases, to the development of a SMg. This may be related to the inflammatory response that occurs after vaccination.
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Huma Sheikh, CEO, NY Neurology Medicine, PC4yrWe are seeing this a lot.
Real-world persistence of erenumab for preventive treatment of chronic and episodic migraine: Retrospective real-world study - PubMed
Source : https://pubmed.ncbi.nlm.nih.gov/34807454/
The majority of patients prescribed erenumab remained persistent for at least a year after treatment initiation, and most patients initiated or escalated to a 140 mg dose. These results suggest...
Conclusions: The majority of patients prescribed erenumab remained persistent for at least a year after treatment initiation, and most patients initiated or escalated to a 140 mg dose. These results suggest that erenumab is well tolerated, and its uptake as a new class of prophylactic treatment for migraine in real-world clinical practice is not...
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Huma Sheikh, CEO, NY Neurology Medicine, PC4yrImportant study.
Smooth muscle ATP-sensitive potassium channels mediate migraine-relevant hypersensitivity in mouse models - PubMed
Source : https://pubmed.ncbi.nlm.nih.gov/34816764/
1 Danish Headache Center, Department of Neurology, Rigshospitalet, University of Copenhagen, Denmark. 2 Novo Nordisk Foundation Center for Protein Research, University of Copenhagen, Denmark. 3 Department of Pharmacy, Faculty of...
Conclusion: Hypersensitivity provoked by GTN and levcromakalim in mice is dependent on functional smooth muscle KATP channels of extracerebral origin. These results suggest a vascular contribution to hypersensitivity induced by migraine triggers.
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Huma Sheikh, CEO, NY Neurology Medicine, PC4yrThe neurovascular connection in migraine is still to be explained.
Chronic migraine reversal and prevention with the LIFE diet: a nutrient dense whole food plant-based diet (WFPBD)
Source : https://casereports.bmj.com/content/14/12/e243987
We report a case of a 60-year-old man who struggled with frequent migraines for 12.5 years, which were refractory to all conventional therapies. Six months before initial consultation, these migraines...
These results far exceed the goal of migraine treatment with medication, which is to reduce migraine frequency by >50% per month. In addition, the results were durable; this patient has been migraine-free for 7.5 years. Serum beta-carotene more than tripled after the patient started the LIFE diet, consistent with its high content of dark...
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Huma Sheikh, CEO, NY Neurology Medicine, PC4yrThis is really interesting.
Napping behavior in adults with episodic migraine: a six-week prospective cohort study
Source : https://doi.org/10.1093/sleep/zsab273
AbstractStudy objectives. Patients with migraine commonly endorse napping as a strategy for headache pain relief, but also experience high rates of sleep distur
Conclusions:Our findings suggest that naps may be an uncommonly used behavioral strategy for prolonged migraine attacks and do not contribute to nightly sleep disturbance. Future studies are needed to examine the acute analgesic effects of daytime napping in patients with migraine.