Metabolic profile changes in serum of migraine patients detected using 1H-NMR spectroscopy - The Journal of Headache and Pain
Source : https://thejournalofheadacheandpain.biomedcentral.com/articles/10.1186/s10194-021-01357-w
Background Migraine is a common brain disorder but reliable diagnostic biomarkers in blood are still lacking. Our aim was to identify, using proton nuclear magnetic resonance (1H-NMR) spectroscopy, metabolites in...
Conclusion: This study indicates that metabolic profiles, based on serum concentrations of several metabolites, including lipids, amino acids and metabolites of glucose metabolism, can distinguish active migraine patients from controls.
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Huma Sheikh, CEO, NY Neurology Medicine, PC4yrThis might help reveal biological identifiers of migraine.
Neuropsychological Profile in Pediatric Migraine without Aura: A Pilot Study
Source : https://doi.org/10.3390/brainsci11121582
Despite the high prevalence of headache in developmental age, current reports about its neuropsychological effects are still lacking. The aim of the present pilot study is to assess the neuropsychological...
MwoA children differed from controls significantly among the NEPSY-2 subscales, with a relevant relationship between the frequency and intensity of the attacks. In conclusion, the results of the present pilot study may suggest that MwoA could impact significantly neuropsychological functioning in children.
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Huma Sheikh, CEO, NY Neurology Medicine, PC4yrWe need similar studies to validate.
Symptomatic Migraine with Prolonged Visual Aura and Unruptured Occipital Arteriovenous Malformation - PubMed
Source : https://pubmed.ncbi.nlm.nih.gov/34841500/
A 35 year-old woman had a two-year history of recurrent headache with clinical presentations of visual aura in her left visual field followed by right-sided throbbing headache. The patient suffered...
The acute vascular flow change and the parenchymal edema trigger a prolonged visual aura with coinstantaneous evidence of cortical depression shown on the electroencephalogram. Keywords: Symptomatic migraine; Prolonged visual aura; Unruptured arteriovenous malformation.
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Huma Sheikh, CEO, NY Neurology Medicine, PC4yrGreat case.
Two-year efficacy and safety of erenumab in participants with episodic migraine and 2-4 prior preventive treatment failures: results from the LIBERTY study
Source : https://jnnp.bmj.com/content/early/2021/11/28/jnnp-2021-327480.abstract
Objective To evaluate individual and group long-term efficacy and safety of erenumab in individuals with episodic migraine (EM) for whom 2-4 prior preventatives had failed. Methods Participants completing the 12-week...
Conclusions: Efficacy was sustained over 112 weeks in individuals with difficult-to-treat EM for whom 2–4 prior migraine preventives had failed. Erenumab treatment was safe and well tolerated, in-line with previous studies.
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Huma Sheikh, CEO, NY Neurology Medicine, PC4yrThese are important results.
Cluster-then-classify methodology for the identification of pain episodes inchronic diseases
Source : https://ieeexplore.ieee.org/abstract/document/9625811
Chronic diseases benefit of the advances on personalize medicine coming out of the integrative convergence of significant developments in systems biology, the Internet of Things and Artificial Intelligence. 70% to...
The migraine is one of the most disabling neurological diseases that affects over 12% of the population worldwide and leads to high economic costs for private and public health systems. This study aims to classify pain episodes by the characterization of pain curves reported by patients in real time. Pain curves have been described as a set of...
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Huma Sheikh, CEO, NY Neurology Medicine, PC4yrMore classification like this is needed.