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4yr
Mindfulness-Based Cognitive Therapy as Migraine Intervention: a Randomized Waitlist Controlled Trial - International Journal of Behavioral Medicine

Mindfulness-Based Cognitive Therapy as Migraine Intervention: a Randomized Waitlist Controlled Trial - International Journal of Behavioral Medicine

Source : https://link.springer.com/article/10.1007/s12529-021-10044-8

Background Based on promising effects seen in a pilot study evaluating a generic mindfulness-based program for migraine, we developed a migraine-specific adaptation of the Mindfulness-Based Cognitive Therapy (MBCT) program. The...


Conclusions: The migraine-specific MBCT program did not result in improvements with regard to headache-related impairment but showed a reduction in headache frequency as well as improved psychological functioning in secondary outcomes.


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4yr
Differentiating Between Migraine and Post-traumatic Headache Using a Machine Learning Classifier

Differentiating Between Migraine and Post-traumatic Headache Using a Machine Learning Classifier

Source : https://n.neurology.org/content/98/1_Supplement_1/S5.2.abstract

Objective The objective was to develop classification models differentiating persistent PTH (PPTH) and migraine using clinical data and MRI-based measures of brain structure and functional connectivity. Background PTH and migraine...


Conclusions: Multivariate models including clinical characteristics, functional connectivity, and brain structural data accurately classify and differentiate PPTH vs migraine.

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4yr
A replication study separates polymorphisms behind migraine with and without depression

A replication study separates polymorphisms behind migraine with and without depression

Source : https://journals.plos.org/plosone/article?id=10.1371/journal.pone.0261477

The largest migraine genome-wide association study identified 38 candidate loci. In this study we assessed whether these results replicate on a gene level in our European cohort and whether effects...


Bayesian relevance analysis confirmed the relevance of intergenic rs6660757 and rs12128399 (p31.1), rs1043215 (REST), rs1889974 (HPSE2) and rs11163394 (ADGRL2) from depression interaction results, and the moderate relevance of rs77864828 and rs2455107 of PRDM16 from main effect analysis. Both main and interaction effect SNPs could enhance...

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4yr

50-year-old female reports having ~10 migraine days per month with some migraine attacks lasting longer than 12 hours. She is currently on topiramate for migraine prevention and has escalated through various acute medications/combinations with  increasing use recently. As a working mother with three school-aged children, her increased absenteeism and presenteeism is causing her substantial anxiety and stress.



Currently, this patient has a BMI of 26 and is post-menopausal.



What treatment(s) would you recommend for this patient? What factors would you consider when deciding how to treat this patient?


  • 4yr
    Possibly use an abortive Rxs, the goal of abortive treatment is to stop a migraine once it starts. Use of CGRP antagonists - rimegepant (Nurtec ODT) and ubrogepant (Ubrelvy) or Show More
  • 4yr
    I would start her on aiMovie do to the number of headaches and the disruption of her life

Show More Comments

  • Saved

4yr

50-year-old female reports having ~10 migraine days per month with some migraine attacks lasting longer than 12 hours. She is currently on topiramate for migraine prevention and has escalated through various acute medications/combinations with  increasing use recently. As a working mother with three school-aged children, her increased absenteeism and presenteeism is causing her substantial anxiety and stress.



Currently, this patient has a BMI of 26 and is post-menopausal.



What treatment(s) would you recommend for this patient? What factors would you consider when deciding how to treat this patient?


  • 4yr
    Possibly use an abortive Rxs, the goal of abortive treatment is to stop a migraine once it starts. Use of CGRP antagonists - rimegepant (Nurtec ODT) and ubrogepant (Ubrelvy) or Show More
  • 4yr
    I would start her on aiMovie do to the number of headaches and the disruption of her life

Show More Comments