Migraine Connect
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A Markov Analysis of Surgical versus Medical Management of Chronic Migraines - PubMed

A Markov Analysis of Surgical versus Medical Management of Chronic Migraines - PubMed

Source : https://pubmed.ncbi.nlm.nih.gov/35311748/

doi: 10.1097/PRS.0000000000009048. Online ahead of print. 1 From the Departments of Plastic and Reconstructive Surgery and Neurosurgery, Johns Hopkins Hospital; and Department of Biomedical Engineering and the Institute for NanoBioTechnology,...


Conclusions: Surgical deactivation of migraine trigger sites may pose a cost-effective approach to treating refractory chronic migraine in adults. This is especially the case when patients are anticipated to require therapy for more than 1 year.

  • 4yr
    Thanks for your contribution, [~Huma--Sheikh--huma927@ ] ! What are the pros or cons to surgery for migraine in your opinion? What has clinician experience been with this strategy?
  • 4yr
    There has always been controversy around surgery for chronic migraine so this is interesting.
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Erenumab for episodic migraine

Erenumab for episodic migraine

Source : https://www.futuremedicine.com/doi/10.2217/pmt-2021-0077

In this review, the authors provide an overview of erenumab, a monoclonal antibody used for the preventative treatment of episodic migraine by targeting the CGRP pathway. Randomized controlled trials have...


Conclusion/Relevance: In this review, the authors provide an overview of erenumab, a monoclonal antibody used for the preventative treatment of episodic migraine by targeting the CGRP pathway. Randomized controlled trials have shown that erenumab is associated with a statistically significant decrease in monthly migraine days in patients with...

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Exploring the contributing factors to multiple chemical sensitivity in patients with migraine - PubMed

Exploring the contributing factors to multiple chemical sensitivity in patients with migraine - PubMed

Source : https://pubmed.ncbi.nlm.nih.gov/35363938/

doi: 10.1002/1348-9585.12328. 1 Department of Neurology, Dokkyo Medical University, Tochigi, Japan. 2 Integrated Research Faculty for Advanced Medical Science, Dokkyo Medical University School of Medicine, Tochigi, Japan. 3 Department of...


Conclusion: We showed that MCS was observed in 20% of patients with migraine, and our study results may indicate a possible association of MCS with central sensitization and hypersensitivity-related symptoms in patients with migraine.

  • 4yr
    Key Points • Source: Journal of Occupational Health • Conclusion/Relevance: “We showed that MCS [multiple chemical sensitivity] was observed in 20% of patients with migraine, and our study results may indicate a Show More
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Association between patent foramen ovale and migraine without aura: a community-based cross-sectional study in China

Association between patent foramen ovale and migraine without aura: a community-based cross-sectional study in China

Source : https://bmjopen.bmj.com/content/12/3/e056937

Objectives To assess the influence of patent foramen ovale (PFO) on the prevalence of migraine without aura based on propensity score-matched samples in Southwest China. Design Propensity-matched cross-sectional study. Participants...


Conclusion:This community-based cross-sectional study pointed to a strong association between PFO and migraine without aura, especially when the shunt is large.

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Erenumab for episodic migraine - PubMed

Erenumab for episodic migraine - PubMed

Source : https://pubmed.ncbi.nlm.nih.gov/35313740/

In this review, the authors provide an overview of erenumab, a monoclonal antibody used for the preventative treatment of episodic migraine by targeting the CGRP pathway. Randomized controlled trials have...


Conclusions: Erenumab faces significant limitations because of its high financial cost. Additional long-term real-world data are needed to understand the role of erenumab in the treatment of migraine.