Fremanezumab in the prevention of high-frequency episodic and chronic migraine: a 12-week, multicenter, real-life, cohort study (the FRIEND study) - PubMed
Source : https://pubmed.ncbi.nlm.nih.gov/35397503/
doi: 10.1186/s10194-022-01396-x. 1 Headache and Pain Unit, IRCCS San Raffaele Pisana, Rome, Italy. [email protected]. 2 San Raffaele University, Rome, Italy. [email protected]. 3 Headache and Pain Unit, IRCCS San Raffaele Pisana,...
Conclusions: Fremanezumab seems more effective in real-life than in RCTs. Younger age emerges as a potential response predictor.
-
Huma Sheikh, CEO, NY Neurology Medicine, PC3yrThis is a great validation study.
Sumatriptan dose increase-induced acute angle closure glaucoma in chronic migraine sufferer - PubMed
Source : https://pubmed.ncbi.nlm.nih.gov/35393301/
1 Ophthalmology, Addenbrooke's Hospital, Cambridge, UK [email protected]. 2 Ophthalmology, Addenbrooke's Hospital, Cambridge, UK. 3 General Surgery, John Radcliffe Hospital, Oxford, UK. 4 Ophthalmology, Epsom and Saint Helier Hospital NHS Trust,...
Conclusion: Sumatriptan dose increase-induced acute angle closure glaucoma in chronic migraine sufferer
-
Huma Sheikh, CEO, NY Neurology Medicine, PC3yrThis is an important indication to be aware of.
New Perspectives for Developing Therapeutic Bioconjugates of Metabolite-Depleting Enzymes: Lessons Learned Combating Glutamate Excitotoxicity
Source : https://pubs.acs.org/doi/10.1021/acs.biomac.2c00117
Glutamate, the main excitatory neurotransmitter in the central nervous system, plays an essential role in several cognitive activities such as memorizing and learning. Excessive glutamate release and disturbance of glutamate...
Conclusion: This Perspective provides an overview of lessons learned by our group when exploring bioconjugate approaches for combatting glutamate excitotoxicity as an illustration of how research on therapeutic bioconjugates is evolving.
Real-world treatment patterns for CGRP mAb | PPA
What was known before? More than 1 in 4 patients with migraine are eligible for migraine preventive treatments, yet around 1 in 10 patients report using them. Conventional preventive treatments...
Conclusion: Patients on CGRP mAb and specifically galcanezumab showed higher adherence and persistence than patients on SOC migraine preventive treatments.
A Markov Analysis of Surgical versus Medical Management of Chronic Migraines - PubMed
Source : https://pubmed.ncbi.nlm.nih.gov/35311748/
doi: 10.1097/PRS.0000000000009048. Online ahead of print. 1 From the Departments of Plastic and Reconstructive Surgery and Neurosurgery, Johns Hopkins Hospital; and Department of Biomedical Engineering and the Institute for NanoBioTechnology,...
Conclusions: Surgical deactivation of migraine trigger sites may pose a cost-effective approach to treating refractory chronic migraine in adults. This is especially the case when patients are anticipated to require therapy for more than 1 year.
-
Migraine Connect3yrThanks for your contribution, [~Huma--Sheikh--huma927@ ] ! What are the pros or cons to surgery for migraine in your opinion? What has clinician experience been with this strategy?
-
Huma Sheikh, CEO, NY Neurology Medicine, PC3yrThere has always been controversy around surgery for chronic migraine so this is interesting.