Early maladaptive schemas differing according to sex may contribute to migraine among the youth
Source : https://www.brainanddevelopment.com/article/S0387-7604(22)00059-6/fulltext
Despite many diverse findings from studies about the comorbidity of psychiatric disorders and migraine, there are still unknown points. Schemas, which are the basic structures of cognition, are understudied. This...
Conclusion: Our study highlights the importance of screening for EMSs among adolescent patients with migraine. Schema therapy and similar therapeutic interventions may be used in the management of migraine in adolescents. Gender may also be important factor the schema therapy in adolescent migraine patients.
Migraine Prevention with Erenumab: Focus on Patient Selection, Perspectives and Outcomes - PubMed
Source : https://pubmed.ncbi.nlm.nih.gov/35411146/
Erenumab is a monoclonal antibody targeting the calcitonin gene-related peptide (CGRP) receptor suitable for episodic and chronic migraine prevention. Randomized clinical trials proved the superiority of erenumab to placebo in...
Conclusions: In the present work, we aimed at reviewing design and results of the main studies on erenumab and discussing treatment use in the current migraine prevention scenario; we also summarized the main ongoing research projects and provided clinical perspectives for the future.
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Huma Sheikh, CEO, NY Neurology Medicine, PC3yrThese are all helpful to make these more viable option.
A real-world, observational study of erenumab for migraine prevention in Canadian patients - PubMed
Source : https://pubmed.ncbi.nlm.nih.gov/35403223/
One-third of patients with EM and CM achieved ≥50% MMD reduction after 3 months of erenumab treatment. This study provides real-world evidence of erenumab effectiveness, safety, and usage for migraine...
Conclusion: One-third of patients with EM and CM achieved ≥50% MMD reduction after 3 months of erenumab treatment. This study provides real-world evidence of erenumab effectiveness, safety, and usage for migraine prevention in adult Canadian patients with multiple prior ineffective prophylactic treatments.
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Huma Sheikh, CEO, NY Neurology Medicine, PC3yrMore validity is great.
Impact of Greater Occipital Nerve Block on Photophobia Levels in Migraine Patients - PubMed
Source : https://pubmed.ncbi.nlm.nih.gov/35421036/
doi: 10.1097/WNO.0000000000001541. Online ahead of print. 1 Neurology Department (JAM, IdL, LS-C, MS, JDdT), University Hospital "La Paz", Madrid, Spain; and La Paz Institute for Health Research (IdiPAZ) (MS, JDdT),...
Conclusions: Greater occipital nerve block improves migraine-associated photophobia, measured with UPSIS-12 and KUMC-8. Patients without aura may exhibit a greater improvement. Physicians could consider GON block for management of photophobia in migraine patients.
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Huma Sheikh, CEO, NY Neurology Medicine, PC3yrYes this a good option esp in pregnancy, but again costs is an issue.
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Dr Hamid3yrGood options for patients such as Greater occipital nerve block improves migraine-associated photophobia
The Arrival of Anti-CGRP Monoclonal Antibodies in Migraine - PubMed
Source : https://pubmed.ncbi.nlm.nih.gov/35426060/
Remarkable advancements have been made in the field of migraine pathophysiology and pharmacotherapy over the past decade. Understanding the molecular mechanism of calcitonin gene-related peptide (CGRP) has led to the...
Conclusion/Relevance: Remarkable advancements have been made in the field of migraine pathophysiology and pharmacotherapy over the past decade. Understanding the molecular mechanism of calcitonin gene-related peptide (CGRP) has led to the discovery of a novel class of drugs, CGRP functional blocking monoclonal antibodies (mAbs), for migraine...
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Huma Sheikh, CEO, NY Neurology Medicine, PC3yrThese are a valuable addition to our tool box, but I hope that insurance companies will catch on.
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Dr Hamid3yrCGRP-targeted mAbs are effective in the preventive treatment of both chronic and episodic migraine