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3yr
Erenumab Impact on Sleep Assessed With Questionnaires and Home-Polysomnography in Patients With Migraine: The ERESON Study

Erenumab Impact on Sleep Assessed With Questionnaires and Home-Polysomnography in Patients With Migraine: The ERESON Study

Source : https://www.frontiersin.org/articles/10.3389/fneur.2022.869677/full

IntroductionMigraine and sleep share a complex and unclear relationship. Poor sleep may trigger migraine attacks; migraine, in turn, is frequently associated with sleep disorders. Few previous studies used questionnaires to...



Conclusion: Our study demonstrated an improvement in both subjective and objective sleep quality in patients treated with a migraine-preventive therapy. Erenumab, in particular, does not cross the blood-brain barrier (BBB), thus a direct effect on sleep is unlikely. Future studies are needed to better understand the mutual influence between...

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3yr
The monoclonal CGRP-receptor blocking antibody erenumab has different effects on brainstem and cortical sensory-evoked responses - PubMed

The monoclonal CGRP-receptor blocking antibody erenumab has different effects on brainstem and cortical sensory-evoked responses - PubMed

Source : https://pubmed.ncbi.nlm.nih.gov/35637558/

Our findings showed that erenumab, in addition to its well-known peripheral effects, can induce central effects earlier in the brainstem and later in the cortex. We cannot rule out whether...



Conclusion: Our findings showed that erenumab, in addition to its well-known peripheral effects, can induce central effects earlier in the brainstem and later in the cortex. We cannot rule out whether these results are due to a direct effect of erenumab on the central nervous system or an indirect effect secondary to peripheral drug modulation.

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3yr
Preview of the 2022 American Headache Society Annual Scientific Meeting

The American Headache Society (AHS) Annual Scientific Meeting is being held in Denver and runs from June 9 to 12, 2022. Participants may also register to attend virtually.


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3yr
Preview of the 2022 American Headache Society Annual Scientific Meeting

The American Headache Society (AHS) Annual Scientific Meeting is being held in Denver and runs from June 9 to 12, 2022. Participants may also register to attend virtually.

  • Saved

3yr
Preview of the 2022 American Headache Society Annual Scientific Meeting

The American Headache Society (AHS) Annual Scientific Meeting is being held in Denver and runs from June 9 to 12, 2022. Participants may also register to attend virtually.