Behavioral and psychological factors in individuals with migraine without psychiatric comorbidities - The Journal of Headache and Pain
Source : https://thejournalofheadacheandpain.biomedcentral.com/articles/10.1186/s10194-022-01485-x
Background It is well known that the course of migraine is influenced by comorbidities and that individual psychological characteristics may impact on the disease. Proper identification of psychological factors that...
Conclusions: Even in individuals without psychiatric comorbidities, specific behavioral and psychological factors are associated with migraine, especially in its chronic form. Proper identification of those factors is important to improve management of migraine through non-pharmacological strategies.
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Huma Sheikh, CEO, NY Neurology Medicine, PC3yrThese are very co-morbid and need attention.
Nummular headache responsive to anti-calcitonin gene-related peptide monoclonal antibodies in a patient with migraine - PubMed
Source : https://pubmed.ncbi.nlm.nih.gov/36018002/
doi: 10.1111/head.14372. Online ahead of print. 1 Department of Neurology, Hospital Reina Sofía, Tudela, Navarra, Spain. 2 Aragon Institute for Health Research (IIS Aragon), Zaragoza, Spain. 3 Neurology Department, Donostia...
Conclusions: Monoclonal antibodies against calcitonin gene-related peptide (CGRP), in particular galcanezumab, might be an effective therapy in some patients with NH. CGRP may have a role in the etiopathogenesis of this headache, which warrants further investigation.
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Huma Sheikh, CEO, NY Neurology Medicine, PC3yrThis lends itself to nummular headache to migraine.
Outpatient Approach to Resistant and Refractory Migraine in Children and Adolescents: a Narrative Review - PubMed
Source : https://pubmed.ncbi.nlm.nih.gov/36018499/
In this review, we summarize the level of evidence for a variety of acute and preventive treatment options to consider in children and adolescents with resistant or refractory migraine. We...
Relevance: In this review, we summarize the level of evidence for a variety of acute and preventive treatment options to consider in children and adolescents with resistant or refractory migraine.
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Huma Sheikh, CEO, NY Neurology Medicine, PC3yrThis is a good review, need more guidance in children.
The Role of High-Conductance Calcium Activated Potassium Channel in Headache and Migraine Pathophysiology - PubMed
Source : https://pubmed.ncbi.nlm.nih.gov/36028922/
Migraine is a common, neurovascular headache disorder with a complex molecular interplay. The involvement of ion channels in the pathogenesis of migraine gathered considerable attention with the findings that different...
Relevance: Recent clinical research revealed that infusion of BKCa channel opener MaxiPost caused vasodilation, headache and migraine attack. Thus, BKCa channel is involved in pathophysiological mechanisms underlying headache and migraine, and targeting BKCa channel presents a new potential strategy for migraine treatment.
Efficacy and Tolerability of Erenumab for Prevention of Episodic Migraine in India - PubMed
Source : https://pubmed.ncbi.nlm.nih.gov/35936611/
1 Department of Neurology, Govind Ballabh Pant Hospital, New Delhi, India. 2 Department of Neurology, Yashoda Hospital, Hyderabad, Telangana, India. 3 Department of Neurology, Calcutta Medical Research Centre, Kolkata, West...
Conclusion: Both doses of erenumab showed numerical improvement for efficacy endpoints and were well-tolerated in the Indian population. No new safety signals were reported.