Migraine Connect
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Gestational exposure to erenumab-The outcome of three pregnancies - PubMed

Gestational exposure to erenumab-The outcome of three pregnancies - PubMed

Source : https://pubmed.ncbi.nlm.nih.gov/36151771/

Erenumab is a monoclonal antibody (mAb) approved for the preventive treatment of migraine. While preclinical studies on calcitonin gene-related peptide mAbs did not identify any reproductive toxicity, pregnant and breastfeeding...


Conclusion/Relevance: No plausible explanation relates the mechanism of action of erenumab and the serious complication that occurred in one patient. Continuous follow-up and reporting of all exposures are encouraged to gather safety data on pregnant and nursing women and on the development of the newborns. So far, immediately stopping the drug...

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Assessment and characteristics of Erenumab therapy on migraine management

Assessment and characteristics of Erenumab therapy on migraine management

Source : https://www.sciencedirect.com/science/article/pii/S1319016422001621?via=ihub

Migraine is one of the neurological diseases that have a negative impact on subjects' productivity and daily activity of patients. Introducing monoclonal antibodies as a valuable option for resolving the...


Conclusion: Using Erenumab therapy showed a great beneficial impact regarding the reduction of migraine-related disabilities. COVID-19 was related to the increased severity of migraine attacks.

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Altered static functional network connectivity predicts the efficacy of non-steroidal anti-inflammatory drugs in migraineurs without aura

Altered static functional network connectivity predicts the efficacy of non-steroidal anti-inflammatory drugs in migraineurs without aura

Source : https://www.frontiersin.org/articles/10.3389/fnmol.2022.956797/full

Brain networks have significant implications for the understanding of migraine pathophysiology and prognosis. This study aimed to investigate whether large-scale network dysfunction in patients with migraine without aura (MwoA) could...


Relevance: Brain networks have significant implications for the understanding of migraine pathophysiology and prognosis. This study aimed to investigate whether large-scale network dysfunction in patients with migraine without aura (MwoA) could predict the efficacy of non-steroidal anti-inflammatory drugs (NSAIDs).

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A stated preference survey to explore patient preferences for novel preventive migraine treatments - PubMed

A stated preference survey to explore patient preferences for novel preventive migraine treatments - PubMed

Source : https://pubmed.ncbi.nlm.nih.gov/36047857/

In this DCE assessing CGRP inhibitors attributes, the main driver of patient choice was treatment effectiveness, specifically reduced migraine severity, and consistent treatment effectiveness. Further, patients exhibited an overall preference...


Conclusion: In this DCE assessing CGRP inhibitors attributes, the main driver of patient choice was treatment effectiveness, specifically reduced migraine severity, and consistent treatment effectiveness. Further, patients exhibited an overall preference for an oral tablet every other day over injectables. Patients' experience with previous...

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Risk factors of vestibular migraine-related brain white matter lesions - Acta Neurologica Belgica

Risk factors of vestibular migraine-related brain white matter lesions - Acta Neurologica Belgica

Source : https://link.springer.com/article/10.1007/s13760-022-02076-y

Objective and purpose Migraine is related to white matter lesions (WMLs), and attack frequency and duration in migraine patients are thought to increase WMLs. However, the relationship between vestibular migraine...


Conclusion: These results substantiate that vertigo frequency is an independent risk factor for WMLs in VM. A high frequency of vertigo episodes is more likely to be associated with WMLs than a low frequency. These results suggest a possible approach to the prevention of WMLs in VM patients.