Assessment and characteristics of Erenumab therapy on migraine management
Source : https://www.sciencedirect.com/science/article/pii/S1319016422001621?via=ihub
Migraine is one of the neurological diseases that have a negative impact on subjects' productivity and daily activity of patients. Introducing monoclonal antibodies as a valuable option for resolving the...
Conclusion: Using Erenumab therapy showed a great beneficial impact regarding the reduction of migraine-related disabilities. COVID-19 was related to the increased severity of migraine attacks.
Altered static functional network connectivity predicts the efficacy of non-steroidal anti-inflammatory drugs in migraineurs without aura
Source : https://www.frontiersin.org/articles/10.3389/fnmol.2022.956797/full
Brain networks have significant implications for the understanding of migraine pathophysiology and prognosis. This study aimed to investigate whether large-scale network dysfunction in patients with migraine without aura (MwoA) could...
Relevance: Brain networks have significant implications for the understanding of migraine pathophysiology and prognosis. This study aimed to investigate whether large-scale network dysfunction in patients with migraine without aura (MwoA) could predict the efficacy of non-steroidal anti-inflammatory drugs (NSAIDs).
A stated preference survey to explore patient preferences for novel preventive migraine treatments - PubMed
Source : https://pubmed.ncbi.nlm.nih.gov/36047857/
In this DCE assessing CGRP inhibitors attributes, the main driver of patient choice was treatment effectiveness, specifically reduced migraine severity, and consistent treatment effectiveness. Further, patients exhibited an overall preference...
Conclusion: In this DCE assessing CGRP inhibitors attributes, the main driver of patient choice was treatment effectiveness, specifically reduced migraine severity, and consistent treatment effectiveness. Further, patients exhibited an overall preference for an oral tablet every other day over injectables. Patients' experience with previous...
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Huma Sheikh, CEO, NY Neurology Medicine, PC3yrVery interesting.
Risk factors of vestibular migraine-related brain white matter lesions - Acta Neurologica Belgica
Source : https://link.springer.com/article/10.1007/s13760-022-02076-y
Objective and purpose Migraine is related to white matter lesions (WMLs), and attack frequency and duration in migraine patients are thought to increase WMLs. However, the relationship between vestibular migraine...
Conclusion: These results substantiate that vertigo frequency is an independent risk factor for WMLs in VM. A high frequency of vertigo episodes is more likely to be associated with WMLs than a low frequency. These results suggest a possible approach to the prevention of WMLs in VM patients.
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Huma Sheikh, CEO, NY Neurology Medicine, PC3yrThis needs more research.
Real-World Patient Experience of CGRP-Targeting Therapy for Migraine: a Narrative Review - Current Pain and Headache Reports
Source : https://link.springer.com/article/10.1007/s11916-022-01077-z
Purpose of Review To summarize available calcitonin gene-related peptide (CGRP)-targeting therapies for migraine and discuss their use in real-world populations. Background CGRP has long been a topic of interest in...
Recent findings and summary: Overall, studies reporting real-world patient experiences of CGRP-targeting therapies suggested meaningful effectiveness for migraine treatment with response rates comparable to the numbers reported in clinical trials. Furthermore, studies suggested benefit in patients with multiple prior unsuccessful treatment...
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Huma Sheikh, CEO, NY Neurology Medicine, PC3yralways need more real world experience.