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Migraine as an inflammatory disorder with microglial activation as a prime candidate

Migraine as an inflammatory disorder with microglial activation as a prime candidate

Source : https://www.tandfonline.com/doi/abs/10.1080/01616412.2022.2129774?journalCode=yner20

ABSTRACT The lower threshold of neuronal hyperexcitability has been correlated with migraines for decades but as technology has progressed, it has now become conceivable to learn more about the migraine...


Results & Conclusion: Of 1136 articles found initially and screening of 1047 records, 47 studies were included for the final review. This review concluded that inflammation and microglial overexpression as the prime candidate, plays an important role in the modulation of migraine and are responsible for the progression toward...

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How can we improve migraine diagnosis?

As few as half of all patients reporting migraine-like symptoms have been formally diagnosed with migraine headaches. Underdiagnosis and treatment may be due to atypical presentation with lack of the best-known symptoms of migraine. Migraines can also mimic other neurological, ocular, or even gastrointestinal conditions. Many patients with migraines are misdiagnosed with sinusitis or tension-type headaches, or suspected of having glaucoma, meningitis, epilepsy, a stroke, brain aneurysm, or a malignancy in the brain.  

In making your diagnosis, how do you differentiate between migraine and those neurological conditions that share similar symptoms?  How do you think more migraine patients can receive a correct diagnosis? 

  • 3yr
    It is important to rule out secondary causes but it will most likely be migraine given how frequent and different the symptoms can be.
  • 3yr
    We have always been taught since medical school and residency training to always rule out other serious causes of whatever symptom the patient is experiencing be it lets say headache, Show More

Show More Comments

  • Saved
How can we improve migraine diagnosis?

As few as half of all patients reporting migraine-like symptoms have been formally diagnosed with migraine headaches. Underdiagnosis and treatment may be due to atypical presentation with lack of the best-known symptoms of migraine. Migraines can also mimic other neurological, ocular, or even gastrointestinal conditions. Many patients with migraines are misdiagnosed with sinusitis or tension-type headaches, or suspected of having glaucoma, meningitis, epilepsy, a stroke, brain aneurysm, or a malignancy in the brain.  



In making your diagnosis, how do you differentiate between migraine and those neurological conditions that share similar symptoms?  How do you think more migraine patients can receive a correct diagnosis? 


  • 3yr
    It is important to rule out secondary causes but it will most likely be migraine given how frequent and different the symptoms can be.
  • 3yr
    We have always been taught since medical school and residency training to always rule out other serious causes of whatever symptom the patient is experiencing be it lets say headache, Show More

Show More Comments

  • Saved
How can we improve migraine diagnosis?

As few as half of all patients reporting migraine-like symptoms have been formally diagnosed with migraine headaches. Underdiagnosis and treatment may be due to atypical presentation with lack of the best-known symptoms of migraine. Migraines can also mimic other neurological, ocular, or even gastrointestinal conditions. Many patients with migraines are misdiagnosed with sinusitis or tension-type headaches, or suspected of having glaucoma, meningitis, epilepsy, a stroke, brain aneurysm, or a malignancy in the brain.  



In making your diagnosis, how do you differentiate between migraine and those neurological conditions that share similar symptoms?  How do you think more migraine patients can receive a correct diagnosis? 


  • 3yr
    It is important to rule out secondary causes but it will most likely be migraine given how frequent and different the symptoms can be.
  • 3yr
    We have always been taught since medical school and residency training to always rule out other serious causes of whatever symptom the patient is experiencing be it lets say headache, Show More

Show More Comments

  • Saved
How can we improve migraine diagnosis?

As few as half of all patients reporting migraine-like symptoms have been formally diagnosed with migraine headaches. Underdiagnosis and treatment may be due to atypical presentation with lack of the best-known symptoms of migraine. Migraines can also mimic other neurological, ocular, or even gastrointestinal conditions. Many patients with migraines are misdiagnosed with sinusitis or tension-type headaches, or suspected of having glaucoma, meningitis, epilepsy, a stroke, brain aneurysm, or a malignancy in the brain.  



In making your diagnosis, how do you differentiate between migraine and those neurological conditions that share similar symptoms?  How do you think more migraine patients can receive a correct diagnosis? 


  • 3yr
    It is important to rule out secondary causes but it will most likely be migraine given how frequent and different the symptoms can be.
  • 3yr
    We have always been taught since medical school and residency training to always rule out other serious causes of whatever symptom the patient is experiencing be it lets say headache, Show More

Show More Comments