Dual therapy with Erenumab and onabotulinumtoxinA: no synergistic effect in chronic migraine -A retrospective cohort study - PubMed
Source : https://pubmed.ncbi.nlm.nih.gov/36507609/
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Conclusions: Our findings suggest that dual therapy is less effective than erenumab alone. However, since the design has multiple limitations, further prospective studies are required to validate these data.
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Huma Sheikh, CEO, NY Neurology Medicine, PCJanuary 09, 2023This is disappointing.
Evaluation of a Polyherbal Formulation on the Management of Migraine Headaches due to Functional Dyspepsia: A Double-Blind, Randomized, Placebo-Controlled Clinical Trial
Source : https://www.hindawi.com/journals/ecam/2022/9872933/
A holistic concept based on traditional Persian medicine (TPM) describes a headache with a gastrointestinal (GI) origin (gastric-headache). Although the neurological manifestations of this headache are similar to those of...
Conclusions: The polyherbal formulation alone may improve the symptoms of migraine patients and other groups. This effect could be due to improving digestion and FD in migraine patients.
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Huma Sheikh, CEO, NY Neurology Medicine, PCJanuary 09, 2023The gut-brain axis is so interesting.
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Dr HamidDecember 21, 2022functional dyspepsia (FD) is a relapsing and remitting disorder characterized by upper abdominal discomfort, early satiety, postprandial abdominal distension, nausea, vomiting, and anorexia, according to ROME III and Parkman’s criteria
Efficacy of the Digital Therapeutic sinCephalea in the prophylaxis of migraine in patients with episodic migraine: study protocol for a digital, randomized, open-label, standard treatment controlled trial - PubMed
Source : https://pubmed.ncbi.nlm.nih.gov/36510284/
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Conclusions: To our knowledge, this is the first systematic clinical trial with a fully digital program to enable patients with migraine to follow a personalized low-glycemic nutrition in order to reduce their number of migraine days and the migraine-induced impact on daily life. Designing a clinical study using a digital intervention includes some obstacles, which are addressed in this study approach.
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Huma Sheikh, CEO, NY Neurology Medicine, PCJanuary 09, 2023Very interesting.
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Dr HamidDecember 21, 2022Emerging evidence shows that CGM-based personalized nutritional recommendations are of prophylactic use in episodic migraine
Migraine severity, disability, and duration: Is a good diet quality, high intake of phytochemicals and polyphenols important?
Source : https://www.frontiersin.org/articles/10.3389/fnut.2022.1041907/full
ObjectivesDietary pattern may be the determinant of migraine prognosis through various mechanisms such as systemic inflammation, vasodilation, cerebral glucose metabolism, and mitochondrial dysfunction.This study was conducted to examine the relationship...
Conclusions: A high-quality diet rich in phytochemicals and polyphenols (especially flavanones and lignans) is associated with low migraine severity. Lower intake of phenols and flavonoids from vegetable oil, olive oil, fruits, and vegetables were associated with more severe migraine attacks. Examination of migraine characteristics and dietary pattern together with phytochemical and polyphenol intake may guide the development of dietary strategies to be used in migraine patients.
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Huma Sheikh, CEO, NY Neurology Medicine, PCJanuary 09, 2023Diet is a big factor in migraine.
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Dr HamidDecember 21, 2022This study was conducted to examine the relationship of the symptoms and signs of migraine with dietary polyphenols and the phytochemical intake and the quality of the diet.
Cerebral perfusion variance in new daily persistent headache and chronic migraine: an arterial spin-labeled MR imaging study - PubMed
Source : https://pubmed.ncbi.nlm.nih.gov/36482334/
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Huma Sheikh, CEO, NY Neurology Medicine, PCJanuary 09, 2023Hope we can use this clinically.
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Dr HamidDecember 21, 2022This study aimed to investigate the cerebral perfusion variances of NDPH and CM using multi-delay pseudo-continuous arterial spin-labeled magnetic resonance imaging (pCASL-MRI).