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A genetic interaction of NRXN2 with GABRE, SYT1 and CASK in migraine patients: a case-control study

A genetic interaction of NRXN2 with GABRE, SYT1 and CASK in migraine patients: a case-control study

Source : https://thejournalofheadacheandpain.biomedcentral.com/articles/10.1186/s10194-021-01266-y

Background Migraine is a multifactorial disorder that is more frequent (two to four times) in women than in men. In recent years, our research group has focused on the role of neurotransmitter release and its regulation. Neurexin (NRXN2) is one of the components of the synaptic vesicle machinery, responsible for connecting intracellular fusion proteins and synaptic vesicles.

  • June 26, 2021
    gene interactions, which may be a part of a larger network, can potentially help us in better understanding migraine aetiology and in development of new therapeutic approaches
  • June 24, 2021
    It is great that the migraine genetics are starting to be revealed.