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Cognitive and emotional impairment in patients with migraine and signs of leukoencephalopathy during preventive therapy | Pozhidaev | Neurology, Neuropsychiatry, Psychosomatics

Cognitive and emotional impairment in patients with migraine and signs of leukoencephalopathy during preventive therapy | Pozhidaev | Neurology, Neuropsychiatry, Psychosomatics

Source :

https://nnp.ima-press.net/nnp/article/view/1467

1. Stovner LJ, Hagen K, Jensen R, et al. The global burden of headache: a documentation of headache prevalence and disability worldwide. Cephalalgia. 2007 Mar;27(3):193- 210. doi: 10.1111/j.1468-2982.2007.01288.x 2. Vos T, Flaxman AD, Naghavi M, et al. Years lived with disability (YLDs) for 1160 sequelae of 289 diseases and injuries 1990-2010: a systematic analysis for the Global Burden of Disease Study 2010.

  • 2 weeks 1 day
    Interesting study suggesting that those with migraine, especially chronic migraine have both cognitive deficits (subtle) and emotional issues; both of which improve with effective treatment of migraine. Improvement in associated symptoms with improved headache control is not a new finding. It would have been helpful to have an arm including patients with migraine without MRI abnormalities since I am not sure that the MRI findings were relevant to the results (but certainly are common in patients with migraine).
  • 2 weeks 6 days
    This is a very interesting study that highlights the fact that migraine is more than just a headache. There are objective measurable cognitive impairment that can come with it, not just due to pain but the overall disease. I wonder if the leukoencephalopathy is the white matter dots that are frequently noted.