Skip to main content
  • Saved

Commented on 's Post

divAbstract

Ultra-fast detection and quantification of nucleic acids by amplification-free fluorescence assay

Ultra-fast detection and quantification of nucleic acids by amplification-free fluorescence assay

Source :

https://pubs.rsc.org/en/content/articlelanding/2020/an/d0an00676a/unauth

Two types of clinically important nucleic acid biomarkers, microRNA (miRNA) and circulating tumor DNA (ctDNA) were detected and quantified from human serum using an amplification-free fluorescence hybridization assay. Specifically, miRNAs hsa-miR-223-3p and hsa-miR-486-5p with relevance for rheumatoid arthritis and cancer related mutations BRAF and KRAS of ctDNA were directly measured.